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Type 1 Cyclic Nucleotide Phosphodiesterases

A CALCIUM and CALMODULIN-dependent cyclic nucleotide phosphodiesterase subfamily. The three members of this family are referred to as type 1A, type 1B, and type 1C and are each product of a distinct gene. In addition, multiple enzyme variants of each subtype can be produced due to multiple alternative mRNA splicing. Although the type 1 enzymes are classified as 3',5'-cyclic-AMP phosphodiesterases (EC 3.1.4.17), some members of this class have additional specificity for CYCLIC GMP.
Also Known As:
Cyclic Nucleotide Phosphodiesterases, Type 1; Ca(2+)-CaM-Stimulated PDE; Ca++ Calmodulin Dependent Cyclic AMP Phosphodiesterase; Ca-CaM-Phosphodiesterase; Calcium-Calmodulin-Dependent Phosphodiesterase; Calcium-Calmodulin-Stimulated Cyclic AMP Phosphodiesterase; Calmodulin Phosphodiesterase; Calmodulin-Dependent Phosphodiesterase; Calmodulin-Dependent cGMP Phosphodiesterase; Cyclic Nucleotide Phosphodiesterase PDE1 Family; Cyclic Nucleotide Phosphodiesterases, Type 1A; Cyclic Nucleotide Phosphodiesterases, Type 1B; Cyclic Nucleotide Phosphodiesterases, Type 1C; PDE1 Phosphodiesterases; Phosphodiesterase 1A, Calmodulin-Dependent; Phosphodiesterase 1B, Calmodulin-Dependent; Phosphodiesterase 1C, Calmodulin-Dependent; Ca CaM Phosphodiesterase; Calcium Calmodulin Dependent Phosphodiesterase; Calcium Calmodulin Stimulated Cyclic AMP Phosphodiesterase; Calmodulin Dependent Phosphodiesterase; Calmodulin Dependent cGMP Phosphodiesterase; Calmodulin-Dependent Phosphodiesterase 1A; Calmodulin-Dependent Phosphodiesterase 1B; Calmodulin-Dependent Phosphodiesterase 1C; Phosphodiesterase 1A, Calmodulin Dependent; Phosphodiesterase 1B, Calmodulin Dependent; Phosphodiesterase 1C, Calmodulin Dependent; Phosphodiesterase, Calcium-Calmodulin-Dependent; Phosphodiesterase, Calmodulin-Dependent cGMP; Phosphodiesterases, PDE1; cGMP Phosphodiesterase, Calmodulin-Dependent; Cyclic Nucleotide Phosphodiesterases, Type I
Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Vas, Adám: 1 article (11/2005)
2. Gulyás, Balázs: 1 article (11/2005)
3. Sharma, Rajendra K: 1 article (10/2005)
4. Das, Shankar B: 1 article (10/2005)
5. Lupi, F: 1 article (10/2004)
6. Barile, L: 1 article (10/2004)
7. Messina, E: 1 article (10/2004)
8. Giacomello, A: 1 article (10/2004)

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