|1.||Iqbal, Khalid: 16 articles (01/2015 - 09/2003)|
|2.||Grundke-Iqbal, Inge: 15 articles (01/2015 - 09/2003)|
|3.||Wang, Jian-Zhi: 11 articles (01/2014 - 09/2004)|
|4.||Zhuang, Zhengping: 10 articles (07/2015 - 07/2009)|
|5.||Li, Wei: 8 articles (03/2014 - 05/2011)|
|6.||Vitek, Michael P: 7 articles (12/2015 - 02/2011)|
|7.||Cristóbal, Ion: 7 articles (08/2015 - 04/2012)|
|8.||Chen, Kuen-Feng: 7 articles (01/2015 - 04/2012)|
|9.||Wang, Qun: 7 articles (01/2014 - 09/2008)|
|10.||Sontag, Estelle: 7 articles (01/2014 - 03/2003)|
|1.||Thymoma (Thymic Carcinoma)
11/01/2012 - "Our data show that in lean Pkr(-/-) mice, there is an improvement in insulin sensitivity, and in glucose tolerance, and a reduction in fasting blood glucose, probably related to a decrease in protein phosphatase 2A activity and a parallel increase in insulin-induced thymoma viral oncogene-1 (Akt) phosphorylation. "
|2.||Muscle Spasticity (Spastic)
12/01/1995 - "Values of mean activity of protein phosphatase 2A in cytosolic extract were 0.90 +/- 0.07 nmol/min per milligram in the control group, 0.75 +/- 0.10 nmol/min per milligram in the spastic group on day 2, and 0.62 +/- 0.17 nmol/min per milligram in the spastic group on day 4 (a significant reduction in protein phosphatase 2A in the spastic group on days 2 and 4). "
01/01/2012 - "Our previous studies confirmed that inhibition of protein phosphatase 2A (PP2A) may provide a promising therapeutic strategy for cancer. "
07/08/2010 - "Earlier studies have shown both p53-dependent and -independent tumor-suppressive functions of B56gamma-specific protein phosphatase 2A (B56gamma-PP2A). "
01/01/2008 - "Earlier studies have demonstrated a functional link between B56gamma-specific protein phosphatase 2A (B56gamma-PP2A) and p53 tumor suppressor activity. "
12/01/2015 - "Taken together, our results suggest that the different responses of normal and tumor cells to low-dose and high-dose radiation depend on AKT activation, which is regulated by protein phosphatase 2 (PP2A). "
08/01/2015 - "Protein phosphatase 2A (PP2A) is a well-known tumor suppressor frequently inhibited in human cancer. "
|4.||Alzheimer Disease (Alzheimer's Disease)
01/01/2015 - "An endogenous inhibitor of protein phosphatase-2A, inhibitor-1, I1PP2A, which inhibits the phosphatase activity by interacting with its catalytic subunit protein phosphatase-2Ac, is known to be upregulated in Alzheimer's disease brain. "
01/01/2015 - "Deficiency of protein phosphatase-2A is a key event in Alzheimer's disease. "
01/01/2015 - "Protein phosphatase-2A (PP2A) deficiency is a cause of the abnormal hyperphosphorylation of tau, which composes neurofibrillary tangles (NFTs) in Alzheimer's disease (AD) brain. "
01/01/2014 - "Increase of inhibitor-2 of protein phosphatase-2A [Formula: see text] is associated with protein phosphatase-2A (PP2A) inhibition and tau hyperphosphorylation in Alzheimer's disease (AD). "
01/01/2014 - "Protein phosphatase 2A dysfunction in Alzheimer's disease."
09/01/2014 - "SET is an endogenous protein phosphatase 2A (PP2A) inhibitor and is associated with a poor prognosis in human leukemia. "
04/15/2014 - "The SET oncoprotein, a potent inhibitor of the protein phosphatase 2A (PP2A), is overexpressed in leukemia. "
09/01/2013 - "Cross talk between p38MAPK and ERK is mediated through MAPK-mediated protein phosphatase 2A catalytic subunit α and MAPK phosphatase-1 expression in human leukemia U937 cells."
12/01/2007 - "Here we show that Jurkat and CCRF-CEM human T-leukemia cell lines were more sensitive than normal human T cells to the cytotoxic effect of inhibiting protein phosphatase 2A (PP2A). "
03/01/2005 - "I-2PP2A/SET, the translocation breakpoint-encoded protein expressed in acute undifferentiated leukemia, was identified as an inhibitor of protein phosphatase 2A (PP2A). "
|3.||Blood Glucose (Blood Sugar)
|4.||Phosphoric Monoester Hydrolases (Phosphatases)
|7.||Proteins (Proteins, Gene)
|8.||Phosphoprotein Phosphatases (Phosphatases, Protein)
|9.||Protein Kinases (Protein Kinase)
|10.||Tumor Viral Antigens (Large T Antigen)
|1.||Drug Therapy (Chemotherapy)
|3.||Heterologous Transplantation (Xenotransplantation)
|5.||Chinese Traditional Medicine (Traditional Chinese Medicine)