Dual Specificity Phosphatase 3

A dual specificity phosphatase subtype that plays a role in intracellular signal transduction by inactivating MITOGEN-ACTIVATED PROTEIN KINASES. It has specificity for EXTRACELLULAR SIGNAL-REGULATED MAP KINASES.

Also Known As:

Dual Specificity Protein Phosphatase 3; H1-Related Protein-Tyrosine Phosphatase; VHR PTPase; Vaccinia Virus H1-Related Protein Tyrosine Phosphatase; H1 Related Protein Tyrosine Phosphatase; PTPase, VHR; Phosphatase, H1-Related Protein-Tyrosine; Protein-Tyrosine Phosphatase, H1-Related; Vaccinia Virus H1 Related Protein Tyrosine Phosphatase

Networked: 10 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Rahmouni, Souad: 4 articles (01/2022 - 02/2015)
2.	Hego, Alexandre: 2 articles (12/2021 - 02/2015)
3.	Jacques, Sophie: 2 articles (12/2021 - 10/2017)
4.	Moutschen, Michel: 2 articles (12/2021 - 02/2015)
5.	Oury, Cécile: 2 articles (12/2021 - 02/2015)
6.	Musumeci, Lucia: 2 articles (10/2017 - 02/2015)
7.	Chen, Yi-Rong: 1 article (06/2022)
8.	Cheng, Chun-Mei: 1 article (06/2022)
9.	Chou, Hsiao-Chin: 1 article (06/2022)
10.	Lin, Tzu-Yin: 1 article (06/2022)

Related Diseases

1.	Vaccinia 10/01/2022 - "Dual-specificity phosphatase 3 (DUSP3), also known as Vaccinia H1-related phosphatase, is a protein tyrosine phosphatase that typically performs its major role in the regulation of multiple cellular functions through the dephosphorylation of its diverse and constantly expanding range of substrates. " 10/01/2000 - "Here we examined the regulatory effects of metal ions on human dual-specificity vaccinia H1-related protein tyrosine phosphatase (VHR) in vitro. " 01/01/2018 - "Vaccinia H1-related phosphatase, also known as dual-specificity phosphatase 3, is a protein tyrosine phosphatase enzyme that regulates the phosphorylation of the mitogen-activated protein kinase signaling pathway, a central mediator of a diversity of biological responses. "
2.	Inflammation (Inflammations) 01/01/2023 - "Dual Specificity Phosphatase 3 (DUSP3) Knockdown Alleviates Acute Myocardial Infarction Damage via Inhibiting Apoptosis and Inflammation." 01/01/2022 - "The genetic deletion of the Dual Specificity Phosphatase 3 (DUSP3) attenuates kidney damage and inflammation following ischaemia/reperfusion injury in mouse."
3.	Carcinogenesis 10/01/2022 - "The role of dual-specificity phosphatase 3 in melanocytic oncogenesis."
4.	Endotoxemia 10/01/2017 - "Dual-Specificity Phosphatase 3 Deletion Protects Female, but Not Male, Mice from Endotoxemia-Induced and Polymicrobial-Induced Septic Shock."
5.	Reperfusion Injury 01/01/2022 - "The genetic deletion of the Dual Specificity Phosphatase 3 (DUSP3) attenuates kidney damage and inflammation following ischaemia/reperfusion injury in mouse."

Related Drugs and Biologics

1.	Mitogen-Activated Protein Kinases
2.	Protein Tyrosine Phosphatases
3.	Phosphoric Monoester Hydrolases (Phosphatases)
4.	Tyrosine (L-Tyrosine)
5.	Proteins (Proteins, Gene)
6.	Phosphotransferases (Kinase)
7.	Metals
8.	Ions
9.	Enzymes