|1.||Sanz, Pascual: 7 articles (12/2015 - 01/2009)|
|2.||Gentry, Matthew S: 6 articles (01/2014 - 06/2005)|
|3.||Romá-Mateo, Carlos: 5 articles (12/2015 - 01/2011)|
|4.||Eng, C: 4 articles (06/2001 - 10/2000)|
|5.||Dukhande, Vikas V: 3 articles (01/2014 - 01/2011)|
|6.||Worby, Carolyn A: 3 articles (04/2012 - 06/2005)|
|7.||Vogt, Andreas: 3 articles (02/2008 - 01/2005)|
|8.||Lazo, John S: 3 articles (02/2008 - 01/2005)|
|9.||Witz, Isaac P: 3 articles (04/2006 - 10/2003)|
|10.||Ganesh, Subramaniam: 3 articles (05/2002 - 03/2002)|
|1.||Melanoma (Melanoma, Malignant)
11/24/2015 - "Ligand-based chemoinformatic discovery of a novel small molecule inhibitor targeting CDC25 dual specificity phosphatases and displaying in vitro efficacy against melanoma cells."
05/15/2004 - "In the present study, we investigated the role of laminin receptor in mediating laminin effects and the involvement of the mitogen-activated protein kinases (MAPK) cascades and dual-specificity phosphatases in laminin signaling in human melanoma cells. "
06/05/2009 - "We hypothesize that attenuation of p38MAPK activity via dephosphorylation by the dual-specificity phosphatase MKP-1 should be protective against ischaemia/reperfusion injury. "
04/09/2004 - "Similarly, transgenic mice overexpressing the p38-inactivating dual specificity phosphatase MAPK phosphatase-1 (MKP-1) were also partially protected, whereas MKP-1 gene-targeted mice showed greater injury after ischemia-reperfusion injury. "
06/01/2015 - "Structure of human dual-specificity phosphatase 7, a potential cancer drug target."
06/01/2014 - "The tumor suppressor protein PTEN is a dual-specificity phosphatase which has protein phosphatase activity and lipid phosphatase activity that antagonizes PI3K activity. "
01/01/2014 - "Expression of dual-specificity phosphatase 5 pseudogene 1 (DUSP5P1) in tumor cells."
05/01/2011 - "Here, we show that expression of the MAPK-specific phosphatase dual-specificity phosphatase-2 (DUSP2) is markedly reduced or completely absent in many human cancers and that its level of expression inversely correlates with that of HIF-1α and with cancer malignancy. "
05/01/2010 - "However, data on dual specificity phosphatase (DPTP) gene mutations in human cancers are lacking. "
|4.||Colorectal Neoplasms (Colorectal Cancer)
11/01/2015 - "Decreased expression of dual specificity phosphatase 22 in colorectal cancer and its potential prognostic relevance for stage IV CRC patients."
01/01/2015 - "A methylation screening assay for DUSP9 (dual-specificity phosphatase 9) has been developed and applied on 79 FFPE samples from patients with colorectal cancer (CRC) and 22 corresponding tumor free colon samples in this study. "
|5.||Pancreatic Neoplasms (Pancreatic Cancer)
01/01/2015 - "Blockade of dual-specificity phosphatase 28 decreases chemo-resistance and migration in human pancreatic cancer cells."
06/01/2003 - "Down-regulation of the dual-specificity phosphatase MKP-1 suppresses tumorigenicity of pancreatic cancer cells."
01/01/2015 - "In the present study, we investigated the role of dual specificity phosphatase 28 (DUSP28) in relation to anti-cancer drug sensitivity and migratory activity in human pancreatic cancer cells for the first time. "
|1.||Protein Kinases (Protein Kinase)
|4.||Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)
|5.||Proto-Oncogene Proteins c-mdm2
|6.||Mitogen-Activated Protein Kinases
|9.||PTEN Phosphohydrolase (PTEN Phosphatase)
|10.||Protein Tyrosine Phosphatases