Class 7 Receptor-Like Protein Tyrosine Phosphatases

A subclass of receptor-like protein tryosine phosphatases that contain a short extracellular domain, a cytosolic kinase-interaction domain, and single protein tyrosine kinase domain.

Also Known As:

Receptor-Like Protein Tyrosine Phosphatases, Class 7; PTPRR Phosphatase; Receptor-Like Protein Tyrosine Phosphatases, Class VII; Phosphatase, PTPRR; Receptor Like Protein Tyrosine Phosphatases, Class 7; Receptor Like Protein Tyrosine Phosphatases, Class VII; Protein Tyrosine Phosphatase, Receptor Type R

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Xu, Qi: 2 articles (02/2012 - 12/2011)
2.	Cao, Jian: 1 article (11/2019)
3.	Chen, Shengmiao: 1 article (11/2019)
4.	Fan, Gaofeng: 1 article (11/2019)
5.	Hao, Piliang: 1 article (11/2019)
6.	Hou, Linjun: 1 article (11/2019)
7.	Li, Dake: 1 article (11/2019)
8.	Liu, Weiwei: 1 article (11/2019)
9.	Wang, Yuetong: 1 article (11/2019)
10.	Wang, Zuo: 1 article (11/2019)

Related Diseases

1.	Major Depressive Disorder (Major Depressive Disorders) 02/01/2012 - "Gender-specific role of the protein tyrosine phosphatase receptor type R gene in major depressive disorder." 12/01/2011 - "To explore the genetic association between protein tyrosine phosphatase receptor type R (PTPRR) gene polymorphism and major depressive disorder (MDD) and its endophenotype. " 12/01/2011 - "[Association between protein tyrosine phosphatase receptor type R gene and major depressive disorder]."
2.	Carcinogenesis 12/16/2009 - "The protein tyrosine phosphatase receptor type R gene is an early and frequent target of silencing in human colorectal tumorigenesis."
3.	Ovarian Neoplasms (Ovarian Cancer) 11/29/2019 - "Here, we found that protein tyrosine phosphatase receptor type R (PTPRR) suppressed the activation of the Wnt/β-catenin pathway in ovarian cancer. " 11/29/2019 - "Protein tyrosine phosphatase receptor type R (PTPRR) antagonizes the Wnt signaling pathway in ovarian cancer by dephosphorylating and inactivating β-catenin."
4.	Hirschsprung Disease (Hirschsprung's Disease) 01/01/2019 - "Downregulation of Protein Tyrosine Phosphatase Receptor Type R Accounts for the Progression of Hirschsprung Disease."
5.	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/03/2013 - "Using methyl-DNA immunoprecipitation coupled with microarray analysis, we found that the protein tyrosine phosphatase receptor type R (PTPRR) was silenced through DNMT3B-mediated methylation in the cervical cancer. "

Related Drugs and Biologics

1.	Catenins
2.	DNA (Deoxyribonucleic Acid)