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Non-Receptor Type 22 Protein Tyrosine Phosphatase

A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of an N-terminal catalytic domain and a C-terminal PROLINE-rich domain. The phosphatase subtype is predominantly expressed in LYMPHOCYTES and plays a key role in the inhibition of downstream T-LYMPHOCYTE activation. Polymorphisms in the gene that encodes this phosphatase subtype are associated with a variety of AUTOIMMUNE DISEASES.
Also Known As:
Protein Tyrosine Phosphatase, Non-Receptor Type 22; Lymphoid Phosphatase; Lyp1 PTPase; Lyp2 PTPase; PTPase Lyp; Protein-Tyrosine Phosphatase Lyp; Tyrosine Protein Phosphatase, Non-Receptor Type 22; PTPase, Lyp1; PTPase, Lyp2; Protein Tyrosine Phosphatase Lyp; Protein Tyrosine Phosphatase, Non Receptor Type 22; Tyrosine Protein Phosphatase, Non Receptor Type 22
Networked: 39 relevant articles (1 outcomes, 2 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Martín, Javier: 2 articles (01/2016 - 01/2013)
2. de la Puerta, María Luisa: 2 articles (09/2014 - 01/2013)
3. Bayón, Yolanda: 2 articles (09/2014 - 01/2013)
4. Sánchez Crespo, Mariano: 2 articles (09/2014 - 01/2013)
5. Alonso, Andrés: 2 articles (09/2014 - 01/2013)
6. Rodríguez, María del Carmen: 2 articles (09/2014 - 01/2013)
7. Trinidad, Antonio G: 2 articles (09/2014 - 01/2013)
8. Løvås, Kristian: 2 articles (04/2009 - 08/2008)
9. Mustelin, Tomas: 2 articles (03/2009 - 04/2004)
10. González-Gay, Miguel A: 1 article (01/2016)

Related Diseases

1. Autoimmune Diseases (Autoimmune Disease)
2. Rheumatoid Arthritis
3. Systemic Lupus Erythematosus (Libman-Sacks Disease)
4. Type 1 Diabetes Mellitus (Autoimmune Diabetes)
5. Thyroid Diseases (Thyroid Disease)

Related Drugs and Biologics

1. Tyrosine (L-Tyrosine)
2. cytotoxic T-lymphocyte antigen 4
3. Contactin 2
4. Protein Isoforms (Isoforms)
5. T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)
6. Complementary DNA (cDNA)
7. T-Cell Antigen Receptors (T-Cell Receptor)
8. Phosphotransferases (Kinase)
9. Interleukin-2 (IL2)
10. Interleukin-1 (Interleukin 1)