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Non-Receptor Type 12 Protein Tyrosine Phosphatase

A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of a N-terminal catalytic domain and a large C-terminal domain that is enriched in PROLINE, GLUTAMIC ACID, SERINE, and THREONINE residues (PEST sequences). The phosphatase subtype is ubiquitously expressed and implicated in the regulation of a variety of biological processes such as CELL MOVEMENT; CYTOKINESIS; focal adhesion disassembly; and LYMPHOCYTE ACTIVATION.
Also Known As:
Protein Tyrosine Phosphatase, Non-Receptor Type 12; PEP PTPase; PEP Protein Tyrosine Phosphatase; PEST-Enriched Phosphatase; PTP-PEST; PEST Enriched Phosphatase; PTPase, PEP; Phosphatase, PEST-Enriched; Protein Tyrosine Phosphatase, Non Receptor Type 12
Networked: 16 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Sastry, Sarita K: 2 articles (02/2014 - 08/2010)
2. Rengifo-Cam, William: 2 articles (02/2014 - 08/2010)
3. Espejo, Rosario: 2 articles (02/2014 - 08/2010)
4. Lu, Zhimin: 2 articles (02/2013 - 11/2011)
5. Zheng, Yanhua: 2 articles (02/2013 - 11/2011)
6. Palmer, Helen E F: 1 article (05/2014)
7. Mashima, Keisuke: 1 article (05/2014)
8. Honda, Reika: 1 article (05/2014)
9. Koizumi, Karen: 1 article (05/2014)
10. Maruyama, Atsuko: 1 article (05/2014)

Related Diseases

1. Neoplasms (Cancer)
2. Neoplasm Metastasis (Metastasis)
3. Leukemia
4. Carcinoma (Carcinomatosis)
5. Breast Neoplasms (Breast Cancer)

Related Drugs and Biologics

1. Small Interfering RNA (siRNA)
2. Tyrosine (L-Tyrosine)
3. Messenger RNA (mRNA)
4. Dynamins (Dynamin)
5. GTP Phosphohydrolases (GTPases)
6. Protein Tyrosine Phosphatases
7. Cadherins (E-Cadherin)
8. Proteins (Proteins, Gene)
9. Insulin (Novolin)
10. Pyogenic arthritis, pyoderma gangrenosum, and acne