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Non-Receptor Type 1 Protein Tyrosine Phosphatase

A subtype of non-receptor protein tyrosine phosphatases that includes two distinctive targeting motifs; an N-terminal motif specific for the INSULIN RECEPTOR, and a C-terminal motif specific for the SH3 domain containing proteins. This subtype includes a hydrophobic domain which localizes it to the ENDOPLASMIC RETICULUM.
Also Known As:
Protein Tyrosine Phosphatase, Non-Receptor Type 1; PTPase 1B; PTPase HA2; Protein Tyrosine Phosphatase 1B; Protein-Tyrosine Phosphatase HA2; Protein Tyrosine Phosphatase HA2; Protein Tyrosine Phosphatase, Non Receptor Type 1
Networked: 194 relevant articles (6 outcomes, 11 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Li, Jia: 9 articles (01/2015 - 10/2006)
2. Tremblay, Michel L: 9 articles (11/2012 - 04/2002)
3. Oh, Won Keun: 8 articles (07/2014 - 02/2006)
4. Neel, Benjamin G: 8 articles (07/2013 - 06/2004)
5. Ahn, Jong Seog: 8 articles (08/2009 - 02/2006)
6. Zhang, Zhong-Yin: 7 articles (11/2014 - 07/2005)
7. Kim, Bo Yeon: 7 articles (08/2009 - 02/2006)
8. Kennedy, Brian P: 7 articles (10/2007 - 02/2002)
9. Bence, Kendra K: 6 articles (12/2015 - 10/2011)
10. Kahn, Barbara B: 6 articles (07/2013 - 06/2004)

Related Diseases

1. Obesity
2. Type 2 Diabetes Mellitus (MODY)
3. Heart Failure
4. Colitis
5. AIDS-Related Complex (ARC)

Related Drugs and Biologics

1. Leptin
2. Non-Receptor Type 2 Protein Tyrosine Phosphatase
3. Pro-Opiomelanocortin (Proopiomelanocortin)
4. Sucrose (Saccharose)
5. NAD (NADH)
6. Hormones
7. Insulin (Novolin)
8. Glucose (Dextrose)
9. Protein-Tyrosine Kinases (Tyrosine Kinase)
10. Streptozocin (Streptozotocin)

Related Therapies and Procedures

1. Therapeutics