Receptor-Like Protein Tyrosine Phosphatases

A subcategory of protein tyrosine phosphatases that are bound to the cell membrane. They contain cytoplasmic tyrosine phosphatase domains and extracellular protein domains that may play a role in cell-cell interactions by interacting with EXTRACELLULAR MATRIX components. They are considered receptor-like proteins in that they appear to lack specific ligands.

Also Known As:

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Azuma, Takeshi: 1 article (09/2005)
2.	De Guzman, Blanquita B: 1 article (09/2005)
3.	Hirayama, Toshiya: 1 article (09/2005)
4.	Hisatsune, Junzo: 1 article (09/2005)
5.	Ito, Yoshiyuki: 1 article (09/2005)
6.	Moss, Joel: 1 article (09/2005)
7.	Nakayama, Masaaki: 1 article (09/2005)
8.	Nishi, Yoshito: 1 article (09/2005)
9.	Ohtani, Masahiro: 1 article (09/2005)
10.	Wada, Akihiro: 1 article (09/2005)

Related Diseases

1.	Hepatocellular Carcinoma (Hepatoma) 03/01/1998 - "The mRNA levels for receptor-like protein tyrosine phosphatases (PTPases), PTPalpha, PTPdelta, PTPgamma and LAR, were evaluated by Northern blot analysis in two types of chemically-induced rat primary hepatomas. "
2.	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 09/01/2005 - "Immunoprecipitation experiments showed that, in AZ-521 cells, activated m2VacA, similar to m1VacA, binds to two receptor-like protein tyrosine phosphatases, RPTPalpha and RPTPbeta suggesting that activated m2VacA as well as m1VacA may contribute to gastrointestinal disease following H. "

Related Drugs and Biologics

1.	Class 5 Receptor-Like Protein Tyrosine Phosphatases
2.	Messenger RNA (mRNA)