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Group IV Phospholipases A2

A cytosolic phospholipase A2 group that plays an important role in the release of free ARACHIDONIC ACID, which in turn is metabolized to PROSTAGLANDINS by the CYCLOOXYGENASE pathway and to LEUKOTRIENES by the 5-LIPOXYGENASE pathway.
Also Known As:
Cytosolic Phospholipase A2 alpha; Cytosolic Phospholipase A2 beta; Cytosolic Phospholipase A2 delta; Cytosolic Phospholipase A2 epsilon; Cytosolic Phospholipase A2 gamma; Group IV Cytosolic Phospholipase A2; Group IVA Phospholipase A2; Group IVA Phospholipases A2; Group IVB Phospholipase A2; Group IVB Phospholipases A2; Group IVC Phospholipase A2; Group IVC Phospholipases A2; Group IVD Phospholipase A2; Group IVD Phospholipases A2; Group IVE Phospholipase A2; Group IVE Phospholipases A2; Group IVF Phospholipase A2; Group IVF Phospholipases A2; PLA(2)-IV; PLA2-IV; Phospholipase A(2)alpha; Phospholipase A2 Group IVA; Phospholipase A2 IV; Phospholipase A2, Group IVB; Phospholipase A2, Group IVC; Phospholipase A2, Group IVD; Phospholipase A2, Group IVE; Phospholipase A2, Group IVF; Phospholipase A2-alpha; Phospholipase A2-beta; Phospholipase A2-gamma; cPLA2-alpha; cPLA2-gamma; Phospholipase A2 alpha; Phospholipase A2 beta; Phospholipase A2 gamma; cPLA2 alpha; cPLA2 gamma; Phospholipases A2, Group IV
Networked: 36 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Sokolowska, Milena: 3 articles (02/2014 - 06/2010)
2. Shimizu, Takao: 3 articles (10/2012 - 09/2005)
3. Sapirstein, Adam: 3 articles (08/2012 - 12/2006)
4. Wu, Tong: 3 articles (02/2008 - 10/2004)
5. Han, Chang: 3 articles (02/2008 - 10/2004)
6. Shelhamer, James H: 2 articles (02/2014 - 10/2004)
7. Pawliczak, Rafal: 2 articles (01/2014 - 06/2010)
8. Uozumi, Naonori: 2 articles (10/2012 - 09/2005)
9. Zhang, Jian: 2 articles (08/2012 - 01/2010)
10. Li, Rung-Chi: 2 articles (08/2012 - 01/2010)

Related Diseases

1. Experimental Arthritis
2. Inflammation
3. Neoplasms (Cancer)
4. Colorectal Neoplasms (Colorectal Cancer)
5. Prostatic Neoplasms (Prostate Cancer)

Related Drugs and Biologics

1. Group IV Phospholipases A2
2. N- ((4- (biphenyl- 2- ylmethoxy)- 1- (2- (4- fluorobenzoyl)benzoyl)pyrrolidin- 2- yl)methyl)- 4- ((2,4- dioxothiazolidin- 5- ylidene)methyl)benzamide
3. Arachidonic Acid (Vitamin F)
4. Cyclooxygenase 2 (Cyclooxygenase-2)
5. Eicosanoids
6. Phosphotransferases (Kinase)
7. Enzymes
8. Calcium
9. Calcium-Independent Phospholipases A2
10. Group X Phospholipases A2

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)