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Cytosolic Phospholipases A2

A subcategory of phospholipases A2 that occur in the CYTOSOL.

Also Known As:

Phospholipases A2, Cytosolic; cPLA2 Phospholipases; Phospholipases, cPLA2

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Esterases: 1574
      - Carboxylic Ester Hydrolases: 62
        Phospholipases: 2589
        Phospholipases A: 58
        Phospholipases A2: 2075
        Cytosolic Phospholipases A2: 4
        Peroxiredoxin VI: 125
        Group IV Phospholipases A2: 60

Experts

1.	Berezhnov, Alexey V: 1 article (10/2020)
2.	Dynnik, Vladimir V: 1 article (10/2020)
3.	Fedotova, Evgeniya I: 1 article (10/2020)
4.	Kasymov, Vitaly A: 1 article (10/2020)
5.	Nenov, Miroslav N: 1 article (10/2020)
6.	Pimenov, Oleg Yu: 1 article (10/2020)
7.	Antonicelli, Frank: 1 article (03/2002)
8.	Aubert, Dominique: 1 article (03/2002)
9.	Bonhomme, Annie: 1 article (03/2002)
10.	Burlet, Henriette: 1 article (03/2002)

Related Diseases

1.	Prolapse 01/01/1998 - "Comparative immunohistochemical study of group II (synovial-type) and group IV (cytosolic) phospholipases A2 in disc prolapse tissue."
2.	Cardiotoxicity 10/10/2020 - "Collectively, PC-driven cardiotoxicity involves: (I) redistribution of Ca2+ from SR to mitochondria with minimal contribution of external calcium influx; (II) irreversible inhibition of Krebs cycle and OXPHOS underlying limited mitochondrial Ca2+ buffering; (III) induction of mPTP reinforced by PC-calcium interplay; (IV) activation of Ca2+-dependent phospholipases cPLA2 and PLC. "
3.	Inflammation (Inflammations) 05/20/1997 - "To define the isoform of phospholipases A2 active in inflammation we evaluated the effects of low-molecular-weight inhibitors of secretory and cytosolic phospholipases A2. "
4.	Infections 03/01/2002 - "Involvement of secretory and cytosolic phospholipases A2 during infection of THP1 human monocytic cells with Toxoplasma gondii. "

Related Drugs and Biologics

1.	Phospholipases A2 (Phospholipase A2)
2.	Protein Isoforms (Isoforms)
3.	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)
4.	Calcium