|1.||Gelb, Michael H: 10 articles (07/2013 - 01/2005)|
|2.||Henderson, William R: 6 articles (07/2013 - 04/2007)|
|3.||Hanasaki, Kohji: 5 articles (01/2012 - 10/2003)|
|4.||Murakami, Makoto: 5 articles (04/2011 - 06/2002)|
|5.||Hallstrand, Teal S: 4 articles (07/2013 - 12/2007)|
|6.||Bollinger, James G: 4 articles (07/2013 - 04/2007)|
|7.||Lai, Ying: 4 articles (07/2013 - 01/2010)|
|8.||Ishii, Toshiharu: 4 articles (04/2011 - 10/2005)|
|9.||Masuda, Seiko: 4 articles (04/2011 - 10/2005)|
|10.||Ishimoto, Yoshikazu: 4 articles (04/2011 - 10/2003)|
04/01/2011 - "Our results suggest that sPLA(2)-X regulates 1) the fertility of spermatozoa, not oocytes, beyond the step of flagellar motility, 2) gastrointestinal phospholipid digestion, perturbation of which is eventually linked to delayed onset of a lean phenotype with reduced adiposity, decreased plasma leptin, and improved muscle insulin tolerance, and 3) neuritogenesis of dorsal root ganglia and the duration of peripheral pain nociception. "
|2.||Asthma (Bronchial Asthma)
01/01/2010 - "This study found that TGM2, a mediator that is novel to asthma pathogenesis, is overexpressed in asthmatic airways and functions to increase sPLA(2)-X enzymatic activity. "
07/01/2013 - "Additional insights into epithelial secreted phospholipase A2 group X in asthma."
07/01/2013 - "Therapies targeting epithelial sPLA2-X may be useful in asthma."
07/01/2013 - "These data reveal a relationship between epithelial-derived sPLA2-X and indirect AHR in asthma and that sPLA2-X serves as an epithelial regulator of inflammatory eicosanoid formation. "
07/01/2013 - "We found that sPLA2-X protein is increased in the airways of patients with asthma and that epithelial-derived sPLA2-X may be increased in association with indirect AHR. "
|3.||Abdominal Aortic Aneurysm
01/01/2012 - "This study tested the hypothesis that sPLA(2)-X in neutrophils may contribute to the pathogenesis of abdominal aortic aneurysms (AAA) using sPLA(2)-X(-/-) mice. "
01/01/2011 - "Group X secretory phospholipase A(2) augments angiotensin II-induced inflammatory responses and abdominal aortic aneurysm formation in apoE-deficient mice."
|4.||Coronary Disease (Coronary Heart Disease)
04/01/2015 - "Observational studies report that secretory phospholipase A2 (sPLA2) activity is a marker for coronary heart disease (CHD) risk, and activity measures are thought to represent the composite activity of sPLA2-IIA, -V, and -X. The aim of this study was to use genetic variants of PLA2G10, encoding sPLA2-X, to investigate the contribution of sPLA2-X to the measure of sPLA2 activity and coronary heart disease (CHD) risk traits and outcome. "
07/01/2013 - "Secreted phospholipase A2 group X (sPLA2-X) plays a key role in regulating eicosanoid formation and the development of inflammation and AHR in murine models. "
11/24/2006 - "These results suggest that sPLA2-X mostly remains inactive under physiological conditions and that its proteolytic activation occurs during inflammation or other as yet unidentified circumstances in vivo."
01/01/2014 - "The step further to understand the role of cytosolic phospholipase A2 alpha and group X secretory phospholipase A2 in allergic inflammation: pilot study."
04/01/2006 - "Because secretory phospholipases are released during inflammation and are regulated by UV irradiation, our data suggest an important role for sPLA2-X in cutaneous pigmentation through the release of LPC."
|3.||Secretory Phospholipases A2
|4.||Arachidonic Acid (Vitamin F)
|5.||Group IV Phospholipases A2
|6.||Group V Phospholipases A2
|7.||Group IB Phospholipases A2
|8.||Protein Isoforms (Isoforms)
|9.||Mucin-1 (CA 15-3 Antigen)