Peroxiredoxin VI

A peroxiredoxin that is a cytosolic bifunctional enzyme. It functions as a peroxiredoxin via a single redox-active cysteine and also contains a Ca2+-independent acidic phospholipase A2 activity.

Also Known As:

Networked: 125 relevant articles (5 outcomes, 15 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Fisher, Aron B: 11 articles (01/2022 - 12/2004)
2.	Hong, Jin Tae: 10 articles (01/2020 - 12/2013)
3.	Feinstein, Sheldon I: 7 articles (01/2022 - 12/2004)
4.	Han, Sang Bae: 7 articles (01/2020 - 01/2014)
5.	Park, Mi Hee: 6 articles (10/2019 - 01/2014)
6.	Lee, Dong Hun: 5 articles (01/2020 - 01/2014)
7.	Yun, Hyung-Mun: 5 articles (01/2017 - 08/2013)
8.	Wang, Yan: 5 articles (11/2011 - 12/2004)
9.	Chatterjee, Shampa: 4 articles (10/2021 - 01/2015)
10.	Dodia, Chandra: 4 articles (10/2021 - 01/2015)

Related Diseases

1.	Brain Ischemia (Cerebral Ischemia) 01/01/2017 - "The role of Peroxiredoxin 6 (Prdx6) in brain ischemia remains unclear. " 01/01/2022 - "Knocking Down Peroxiredoxin 6 Aggravates Cerebral Ischemia-Reperfusion Injury by Enhancing Mitophagy." 01/01/2017 - "Phospholipase A2 of Peroxiredoxin 6 Plays a Critical Role in Cerebral Ischemia/Reperfusion Inflammatory Injury." 06/01/2014 - "Ligustilide ameliorates neuroinflammation and brain injury in focal cerebral ischemia/reperfusion rats: involvement of inhibition of TLR4/peroxiredoxin 6 signaling."
2.	Non-alcoholic Fatty Liver Disease 10/01/2019 - "Peroxiredoxin 6 Confers Protection Against Nonalcoholic Fatty Liver Disease Through Maintaining Mitochondrial Function." 01/01/2023 - "Recently, increasing evidence suggests that peroxiredoxin 6 (PRDX6) is involved in the pathogenesis and progression of NAFLD. "
3.	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/01/2020 - "In this article, we describe a beneficial effect of peroxiredoxin 6 (PRDX6) in a type 1 diabetes mouse model. " 01/01/2021 - "Thymulin and peroxiredoxin 6 have protective effects against streptozotocin-induced type 1 diabetes in mice." 01/01/2020 - "Peroxiredoxin 6 Attenuates Alloxan-Induced Type 1 Diabetes Mellitus in Mice and Cytokine-Induced Cytotoxicity in RIN-m5F Beta Cells."
4.	Neuroinflammatory Diseases 06/01/2014 - "Ligustilide ameliorates neuroinflammation and brain injury in focal cerebral ischemia/reperfusion rats: involvement of inhibition of TLR4/peroxiredoxin 6 signaling." 11/01/2016 - "Proteins involved in mitochondrial dysfunction (paraplegin matrix AAA peptidase subunit, SPG7), neuroinflammation (peroxiredoxin 6, PRDX6), and neuronal death (zinc finger protein 90, ZFP90) were markedly reduced in the CT group compared with the CI group. "
5.	Virus Diseases (Viral Diseases) 10/01/2013 - "Western blot analysis further demonstrated the changes in protein abundance of natural killer enhancing factor and peroxiredoxin 6. These results will be helpful in furthering our understanding of the changes of physiological processes in liver of fish during virus infection. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Circulating Thymic Factor
3.	Streptozocin (Streptozotocin)
4.	ligustilide
5.	Antioxidants
6.	Enzymes
7.	Phospholipases A2 (Phospholipase A2)
8.	Peroxiredoxins
9.	Peroxidase (Myeloperoxidase)
10.	Sulfhydryl Compounds (Thiols)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Neoadjuvant Therapy
3.	Therapeutics
4.	Punctures
5.	Ligation