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Peroxiredoxins

A family of ubiquitously-expressed peroxidases that play a role in the reduction of a broad spectrum of PEROXIDES like HYDROGEN PEROXIDE; LIPID PEROXIDES and peroxinitrite. They are found in a wide range of organisms, such as BACTERIA; PLANTS; and MAMMALS. The enzyme requires the presence of a thiol-containing intermediate such as THIOREDOXIN as a reducing cofactor.
Also Known As:
Alkyl Hydroperoxide Reductase; Alkyl Hydroperoxide Reductase C; Alkyl Hydroperoxide Reductase D; Alkylhydroperoxide Reductase; Mitochondrial Thioredoxin-Dependent Antioxidant Protein SP-22; PRDX3 Peroxidase; Peroxidoxin; Peroxiredoxin 1; Peroxiredoxin 2; Peroxiredoxin 3; Peroxiredoxin 4; Peroxiredoxin 5; Peroxiredoxin I; Peroxiredoxin II; Peroxiredoxin III; Peroxiredoxin IV; Peroxiredoxin V; Peroxiredoxin-4; Protector Protein (Mixed-Function Oxidase Systems); Thiol-Specific Antioxidant Protein; Thioredoxin Peroxidase; Thioredoxin Peroxidase 1; Thioredoxin Peroxidase 2; Thioredoxin Peroxidase PMP20; Thioredoxin-Dependent Peroxide Reductase 1; Thioredoxin-Dependent Peroxide Reductase 2; Hydroperoxide Reductase, Alkyl; Mitochondrial Thioredoxin Dependent Antioxidant Protein SP 22; Thiol Specific Antioxidant Protein; Thioredoxin Dependent Peroxide Reductase 1; Thioredoxin Dependent Peroxide Reductase 2; Peroxiredoxin
Networked: 495 relevant articles (7 outcomes, 42 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Soini, Ylermi: 12 articles (12/2015 - 08/2003)
2. Kinnula, Vuokko L: 9 articles (01/2013 - 03/2002)
3. Yu, Dae-Yeul: 8 articles (01/2015 - 03/2007)
4. Kang, Sang Won: 8 articles (10/2013 - 08/2003)
5. Ishii, Tetsuro: 6 articles (11/2015 - 10/2009)
6. Karihtala, Peeter: 6 articles (09/2015 - 08/2003)
7. Lee, Dong-Seok: 6 articles (03/2015 - 03/2007)
8. Hampton, Mark B: 6 articles (08/2013 - 03/2007)
9. Rhee, Sue Goo: 6 articles (09/2012 - 12/2005)
10. Yang, Hee-Young: 5 articles (01/2015 - 03/2007)

Related Diseases

1. Neoplasms (Cancer)
2. Shock
3. Filarial Elephantiasis (Lymphatic Filariasis)
4. Inflammation
5. Carcinoma (Carcinomatosis)

Related Drugs and Biologics

1. Reactive Oxygen Species (Oxygen Radicals)
2. Antigens
3. Ubiquitin
4. Recombinant Proteins
5. Peroxidase (Myeloperoxidase)
6. Antibodies
7. Nitric Oxide Synthase (NO Synthase)
8. Interleukin-8 (Interleukin 8)
9. Pulmonary Surfactants (Pulmonary Surfactant)
10. Phosphoserine

Related Therapies and Procedures

1. Homologous Transplantation (Allograft)
2. Radiotherapy
3. Drug Therapy (Chemotherapy)
4. Heterologous Transplantation (Xenotransplantation)
5. Caloric Restriction