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p21-Activated Kinases

A family of serine-threonine kinases that bind to and are activated by MONOMERIC GTP-BINDING PROTEINS such as RAC GTP-BINDING PROTEINS and CDC42 GTP-BINDING PROTEIN. They are intracellular signaling kinases that play a role the regulation of cytoskeletal organization.
Also Known As:
Oligophrenin-3; PAK Kinases; PAK-1 Kinase; PAK-2 Kinase; PAK1 Kinase; PAK2 Kinase; PAK3 Kinase; PAK65; Serine-Threonine-Protein Kinase PAK 1; Serine-Threonine-Protein Kinase PAK 3; alpha p21-Activated Kinase; alpha-PAK; beta p21-Activated Kinase; beta-PAK; gamma-PAK; p21-Activated Kinase 1; p21-Activated Kinase 2; p21-Activated Kinase 3; p65(PAK); p65PAK Protein; Kinase, PAK; Kinase, p21-Activated; Kinases, PAK; Kinases, p21-Activated; Oligophrenin 3; PAK 1 Kinase; PAK 2 Kinase; Serine Threonine Protein Kinase PAK 1; Serine Threonine Protein Kinase PAK 3; alpha p21 Activated Kinase; beta p21 Activated Kinase; gamma PAK; p21 Activated Kinase; p21 Activated Kinase 1; p21 Activated Kinase 2; p21 Activated Kinase 3; p21 Activated Kinases; p21-Activated Kinase, beta; PAK Kinase; p21-Activated Kinase
Networked: 492 relevant articles (3 outcomes, 39 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Li, Feng: 21 articles (06/2022 - 08/2002)
2. Kumar, Rakesh: 20 articles (01/2020 - 08/2002)
3. Chernoff, Jonathan: 19 articles (01/2022 - 08/2002)
4. He, Hong: 14 articles (01/2019 - 01/2008)
5. Wang, Jian: 12 articles (06/2022 - 04/2012)
6. Baldwin, Graham S: 11 articles (01/2019 - 01/2008)
7. Baloglu, Erkan: 9 articles (12/2021 - 01/2016)
8. Senapedis, William: 8 articles (12/2021 - 01/2016)
9. Li, Yang: 8 articles (12/2021 - 02/2013)
10. Li, Yanshu: 8 articles (12/2021 - 01/2010)

Related Diseases

1. Neoplasms (Cancer)
2. Hepatocellular Carcinoma (Hepatoma)
3. Breast Neoplasms (Breast Cancer)
4. Stomach Neoplasms (Stomach Cancer)
5. Neoplasm Metastasis (Metastasis)

Related Drugs and Biologics

1. Flavonoids
2. myricetin
3. Proteins (Proteins, Gene)
4. Phosphotransferases (Kinase)
5. p21-Activated Kinases
6. Tamoxifen
7. Mitogen-Activated Protein Kinases
8. Gefitinib (Iressa)
9. Monomeric GTP-Binding Proteins
10. Gemcitabine

Related Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Infant Equipment (Crib)
4. Adjuvant Chemotherapy
5. Traction