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Lim Kinases

Serine protein kinases involved in the regulation of ACTIN polymerization and MICROTUBULE disassembly. Their activity is regulated by phosphorylation of a threonine residue within the activation loop by intracellular signaling kinases such as P21-ACTIVATED KINASES and by RHO KINASE.
Also Known As:
LIM Kinase; LIM Motif-Containing Protein Kinases; LIM-Kinase; Kinase, LIM; Kinases, Lim; LIM Motif Containing Protein Kinases
Networked: 62 relevant articles (0 outcomes, 4 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Bernard, Ora: 7 articles (04/2013 - 06/2003)
2. Olson, Michael F: 6 articles (11/2015 - 06/2007)
3. Chakrabarti, Ratna: 4 articles (01/2011 - 09/2003)
4. Munro, June: 3 articles (11/2015 - 10/2010)
5. Savvateeva-Popova, E V: 3 articles (05/2015 - 06/2004)
6. Grizzle, William E: 3 articles (12/2007 - 09/2003)
7. Yoshioka, Kiyoko: 3 articles (11/2006 - 06/2003)
8. Itoh, Kazuyuki: 3 articles (11/2006 - 06/2003)
9. Shanks, Emma: 2 articles (11/2015 - 01/2015)
10. Croft, Daniel R: 2 articles (11/2015 - 10/2010)

Related Diseases

1. Neoplasms (Cancer)
2. Prostatic Neoplasms (Prostate Cancer)
3. Inflammation
4. Fibrosis (Cirrhosis)
5. Osteosarcoma (Osteogenic Sarcoma)

Related Drugs and Biologics

1. Small Interfering RNA (siRNA)
2. Transforming Growth Factor beta (TGF-beta)
3. Tubulin
4. rho-Associated Kinases
5. Phosphotransferases (Kinase)
6. Proteins (Proteins, Gene)
7. Protein Kinases (Protein Kinase)
8. Fas Ligand Protein (Fas Ligand)
9. Death Domain Receptors
10. Actin-Related Protein 2-3 Complex (Arp2 3 Complex)