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Juvenile Myelomonocytic Leukemia

A leukemia affecting young children characterized by SPLENOMEGALY, enlarged lymph nodes, rashes, and hemorrhages. Traditionally classed as a myeloproliferative disease, it is now considered a mixed myeloproliferative-mylelodysplastic disorder.
Also Known As:
Leukemia, Myelomonocytic, Juvenile; Juvenile Myelomonocytic Leukemias; Leukemia, Juvenile Myelomonocytic; Leukemias, Juvenile Myelomonocytic; Myelomonocytic Leukemia, Juvenile; Myelomonocytic Leukemias, Juvenile; Juvenile Chronic Myelogenous Leukemia
Networked: 173 relevant articles (9 outcomes, 14 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Leukemia
2. Chronic Myelomonocytic Leukemia (Leukemia, Chronic Myelomonocytic)
3. Myeloproliferative Disorders (Myeloproliferative Disorder)
4. Noonan Syndrome (Female Pseudo-Turner Syndrome)
5. Acute Promyelocytic Leukemia

Experts

1. Kojima, Seiji: 9 articles (12/2015 - 10/2006)
2. Locatelli, Franco: 9 articles (04/2015 - 04/2004)
3. Niemeyer, Charlotte M: 9 articles (04/2015 - 01/2005)
4. Manabe, Atsushi: 7 articles (02/2015 - 11/2005)
5. Loh, Mignon L: 6 articles (12/2015 - 04/2013)
6. Muramatsu, Hideki: 6 articles (12/2015 - 03/2009)
7. van den Heuvel-Eibrink, Marry M: 6 articles (07/2015 - 01/2005)
8. Zecca, Marco: 6 articles (09/2014 - 01/2005)
9. Emanuel, Peter D: 5 articles (12/2015 - 06/2002)
10. Flotho, Christian: 5 articles (04/2015 - 06/2007)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Juvenile Myelomonocytic Leukemia:
1. Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
2. monosomy Chromosome 7IBA
3. RetinoidsIBA
4. clofarabine (Clolar)FDA Link
5. Tyrosine (L-Tyrosine)FDA Link
6. Interferon-alpha (Interferon Alfa)FDA Link
7. Non-Receptor Type 11 Protein Tyrosine PhosphataseIBA
8. InterferonsIBA
9. Azacitidine (5 Azacytidine)FDA Link
10. TransferasesIBA

Therapies and Procedures

1. Hematopoietic Stem Cell Transplantation
2. Transplants (Transplant)
3. Transplantation (Transplant Recipients)
4. Stem Cell Transplantation
5. Bone Marrow Transplantation (Transplantation, Bone Marrow)