|1.||Mantzoros, Christos S: 15 articles (08/2012 - 01/2004)|
|2.||Kadowaki, Takashi: 9 articles (02/2013 - 12/2003)|
|3.||Yamauchi, Toshimasa: 9 articles (02/2013 - 12/2003)|
|4.||Tseleni-Balafouta, Sofia: 7 articles (12/2011 - 01/2007)|
|5.||Mitsiades, Nicholas: 5 articles (12/2011 - 01/2007)|
|6.||Williams, Catherine J: 5 articles (03/2008 - 06/2006)|
|7.||Otvos, Laszlo: 4 articles (05/2015 - 01/2011)|
|8.||Surmacz, Eva: 4 articles (05/2015 - 01/2011)|
|9.||Buechler, Christa: 4 articles (10/2013 - 06/2006)|
|10.||Neumeier, Markus: 4 articles (10/2013 - 06/2006)|
05/01/2015 - "Possible new therapeutic approach for obesity-related diseases: Role of adiponectin receptor agonists."
04/01/2014 - "Recently, the small molecule adiponectin receptors (AdipoRs) agonist was discovered and suggested that the agonist is a novel therapeutic target for the treatment of type 2 diabetes linked to obesity in an experimental mouse model. "
01/01/2014 - "Obesity: Adiponectin receptor agonists--possible therapeutic approach?"
02/05/2013 - "Adiponectin receptor as a key player in healthy longevity and obesity-related diseases."
02/01/2013 - "No conclusive evidence for association of polymorphisms in the adiponectin receptor 1 gene, AdipoR1, with common obesity."
|2.||Colonic Neoplasms (Colon Cancer)
09/01/2008 - "We examined the expression of the adiponectin receptors on normal colon mucosa and colon cancer tissues in a human study using real-time RT-PCR, Western blotting and immunohistochemical staining. "
09/01/2008 - "Adiponectin receptors, AdipoR1/AdipoR2, were expressed in normal colon epithelial and colon cancer cells. "
09/01/2008 - "Expression of adiponectin receptors, AdipoR1 and AdipoR2, in normal colon epithelium and colon cancer tissue."
07/01/2010 - "Furthermore, knockdown of adiponectin receptors such as AdipoR1 and AdipoR2 relieved the suppressive effect of adiponectin on the growth of colon cancer cells. "
09/01/2008 - "These results suggest that adiponectin may exert some effects on normal colon epithelium or colon cancer cells directly through adiponectin receptors. "
|3.||Hypertension (High Blood Pressure)
01/01/2015 - "The aim of the study was to find out whether peripheral blood leukocyte adiponectin receptors 1 and 2 (AdipoR1, AdipoR2) protein expression patterns (flow cytometry) differ between the primary hypertension children (n = 57) and healthy controls (n = 19) and if their expression levels are related to selected clinical parameters. "
01/01/2015 - "Expression of Adiponectin Receptors on Peripheral Blood Leukocytes of Hypertensive Children Is Associated with the Severity of Hypertension."
12/28/2011 - "AMP effectively improved hypertension, plasma triglyceride, and HDL-cholesterol, glucose, kidney function parameters, hepatic lipid, enhances plasma nitric oxide, and plasma adiponectin accompanied by the up-regulation of mRNA expression levels of the hepatic adiponectin receptor 2. Single and chronic oral administration of AMP affected the hepatic mRNA expression levels of genes involved in β-oxidation, fatty acid synthesis, and AMP-activated protein kinase. "
02/01/2012 - "Diabetes induced tissue-specific changes in messenger RNAs expression of the following selected genes, which were restored by telmisartan treatment: PPARγ, PPARδ, PPARγ coactivator 1α, adiponectin, adiponectin receptor 1, adiponectin receptor 2, phosphotyrosine binding domain and a pleckstrin homology domain-containing adaptor protein, adenosine monophosphate kinase, and glucose translocator 4. Telmisartan blunted the development of hypertension, insulin resistance, and diabetes in prediabetic Cohen-Rosenthal diabetic hypertensive rats through pleiotropic activity, involving specific gene regulation of target organs."
|4.||Body Weight (Weight, Body)
01/01/2004 - "In summary, 1) MTII is an effective treatment for obesity and related metabolic defects in leptin-resistant (DIO, UCP1-DTA) and leptin-sensitive (ob/ob) mouse models of obesity; 2) the effects of MTII on food intake and body weight are more pronounced in DIO mice than in lean mice; 3) the tachyphylactic effect after prolonged MTII administration appears to be, at least in part, caused by a compensatory upregulation of NPY and AgRP mRNA levels, whereas decreasing leptin levels may play a very minor role in mediating tachyphylaxis; and 4) alterations in adiponectin receptor mRNA expression after fasting or MTII treatment may contribute to altered insulin sensitivity and needs to be studied further."
01/01/2015 - "Studies have come to conflicting conclusions about whether polymorphisms in the adiponectin receptor 1 gene (ADIPOR1) are associated with cancer risk. "
01/01/2014 - "Many studies have indicated possible associations between a polymorphism of adiponectin receptor 1 (ADIPOR1) rs1342387 and risk of cancer, but contradictory results have been reported. "
07/01/2009 - "In a separate study, we also studied for the first time whether adiponectin receptors 1 and 2 are expressed in PC by studying 16 PC tumor tissue samples which were analyzed using immunohistochemistry. "
08/01/2015 - "Two types of adiponectin receptor, AdipoR1 and AdipoR2, have been detected in various cancer tissues such as CRC. "
07/01/2015 - "Adiponectin receptor 1 expression in tumor tissues with the AA genotype was significantly lower than that for other genotypes (mean rank: AA 18.55, AG 25, GG 45.76, p = 0.001). "
|2.||Messenger RNA (mRNA)
|6.||AMP-Activated Protein Kinases
|7.||Adenosine Monophosphate (AMP)
|8.||Nitric Oxide (Nitrogen Monoxide)
|2.||Highly Active Antiretroviral Therapy (HAART)