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Leptin Receptors

Cell surface receptors for obesity factor (LEPTIN), a hormone secreted by the WHITE ADIPOCYTES. Upon leptin-receptor interaction, the signal is mediated through the JAK2/STAT3 pathway to regulate food intake, energy balance and fat storage.
Also Known As:
Receptors, Leptin; LEPR Protein; Leptin Receptor; Leptin Receptor, Large Isoform; Leptin Receptor, Small Isoform; Leptin-Binding Protein; OBRa Receptor; OBRb Receptor; Receptor, Leptin; Leptin Binding Protein; Receptor, OB; Receptor, OBRa; Receptor, OBRb; Antigens, CD295; CD295 Antigens; OB Receptor
Networked: 1202 relevant articles (22 outcomes, 192 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Myers, Martin G: 21 articles (12/2014 - 05/2003)
2. Kastin, Abba J: 12 articles (08/2015 - 02/2008)
3. Hsuchou, Hung: 12 articles (08/2015 - 02/2008)
4. Pan, Weihong: 12 articles (08/2015 - 02/2008)
5. Surmacz, Eva: 9 articles (05/2015 - 03/2006)
6. Chua, Streamson C: 9 articles (12/2013 - 03/2004)
7. Tavernier, Jan: 8 articles (11/2015 - 12/2008)
8. Otvos, Laszlo: 6 articles (05/2015 - 01/2011)
9. Wu, Xiaojun: 6 articles (10/2013 - 07/2011)
10. Morton, Gregory J: 6 articles (09/2013 - 05/2003)

Related Diseases

1. Obesity
2. Breast Neoplasms (Breast Cancer)
3. Hyperglycemia
4. Body Weight (Weight, Body)
5. Insulin Resistance

Related Drugs and Biologics

1. Leptin
2. Protein Isoforms (Isoforms)
3. Neuropeptide Y
4. Pro-Opiomelanocortin (Proopiomelanocortin)
5. Biological Markers (Surrogate Marker)
6. Phosphotransferases (Kinase)
7. Gonadotropin-Releasing Hormone (GnRH)
8. Melatonin
9. Bilirubin
10. STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Highly Active Antiretroviral Therapy (HAART)
3. Bariatric Surgery
4. Ligation
5. Injections