Chemokine CCL1

A CC-type chemokine secreted by activated MONOCYTES and T-LYMPHOCYTES. It has specificity for CCR8 RECEPTORS.

Also Known As:

CC Chemokine Ligand 1; CCL1 Chemokine; Chemokine I-309; Chemokine TCA3; Chemokines CCL1; T Cell Activation 3 Protein; Chemokine I 309; Chemokine, CCL1

Networked: 25 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intercellular Signaling Peptides and Proteins: 29768
    - Cytokines: 164289
      - Chemokines: 24660
        CC Chemokines: 2380
        Chemokine CCL1: 25
        HCC-1(9-74)
        human CCL1 protein
        mouse Ccl1 protein
- Peptides: 82426
  - Intercellular Signaling Peptides and Proteins: 29768
    - Cytokines: 164289
      - Chemokines: 24660
        CC Chemokines: 2380
        Chemokine CCL1: 25
        HCC-1(9-74)
        human CCL1 protein
        mouse Ccl1 protein
Biological Factors: 2472

Experts

1.	Liu, Chang: 3 articles (01/2022 - 01/2021)
2.	Xiao, Yang: 3 articles (01/2022 - 01/2021)
3.	Cui, Bing: 2 articles (10/2021 - 01/2021)
4.	Hu, Zhuo-Wei: 2 articles (10/2021 - 01/2021)
5.	Hua, Fang: 2 articles (10/2021 - 01/2021)
6.	Li, Ke: 2 articles (10/2021 - 01/2021)
7.	Li, Ping-Ping: 2 articles (10/2021 - 01/2021)
8.	Li, Yun-Xuan: 2 articles (10/2021 - 01/2021)
9.	Liu, Shan-Shan: 2 articles (10/2021 - 01/2021)
10.	Lv, Xiao-Xi: 2 articles (10/2021 - 01/2021)

Related Diseases

1.	Cardiovascular Diseases (Cardiovascular Disease) 07/21/2006 - "In the present study, we demonstrated that the chemokine CCL1, notably involved in cardiovascular diseases and inflammatory or allergic processes, constitutes a new molecular target for PAHs. "
2.	Breast Neoplasms (Breast Cancer) 12/20/2018 - "The aim of this study was to identify the role of the two major Treg-attracting chemokines CCL1 and CCL22 in human breast cancer. "
3.	Persistent Infection 10/15/2020 - "In this study, we employed a comprehensive transcriptional/translational profiling strategy to delineate the identities, expression patterns, and dynamic regulation of chemokines produced by murine pathogen-specific TM CD8+TM, and to a lesser extent CD4+TM, are a prodigious source for six select chemokines (CCL1/3/4/5, CCL9/10, and XCL1) that collectively constitute a prominent and largely invariant signature across acute and chronic infections. "
4.	Pulmonary Fibrosis (Fibrosing Alveolitis) 07/01/2023 - "The chemokine CCL1 facilitates pulmonary fibrosis by promoting macrophage migration and M2 polarization." 01/01/2022 - "Chemokine CCL1 as a therapeutic target for pulmonary fibrosis: comments on 'The chemokine CCL1 triggers an AMFR‒SPRY1 pathway that promotes differentiation of lung fibroblasts into myofibroblasts and drives pulmonary fibrosis'." 10/12/2021 - "The chemokine CCL1 triggers an AMFR-SPRY1 pathway that promotes differentiation of lung fibroblasts into myofibroblasts and drives pulmonary fibrosis." 01/01/2021 - "The chemokine CCL1 triggers an AMFR-SPRY1 pathway that promotes differentiation of lung fibroblasts into myofibroblasts and drives pulmonary fibrosis."
5.	Inflammation (Inflammations) 01/01/2021 - "Recruitment of immune cells to the site of inflammation by the chemokine CCL1 is important in the pathology of inflammatory diseases. " 08/01/2007 - "Coordinated involvement of mast cells and T cells in allergic mucosal inflammation: critical role of the CC chemokine ligand 1:CCR8 axis." 04/01/2015 - "Inflammation in atopic dermatitis is mediated in part by the chemokine CCL1 and its receptor, CCR8. " 09/01/2016 - " Patients with KLS and KD subjects shared an inflammatory signature including acute-phase reactants reflecting tumor necrosis factor (TNF)-α biologic activity (soluble TNF receptor I/II) and endothelial/smooth muscle chemokines Ccl1 (Th2), Ccl2 (vascular inflammation), and Cxcl11 (plasma cell recruitment). "

Related Drugs and Biologics

1.	Chemokines
2.	Proteins (Proteins, Gene)
3.	Chemokine CCL4
4.	CCR8 Receptors
5.	Chemokine Receptors
6.	Interleukin-13
7.	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)
8.	Interleukin-10 (Interleukin 10)
9.	Cytokines
10.	Interleukin-4 (Interleukin 4)

Related Therapies and Procedures

1.	Moxibustion