|1.||Kuziel, William A: 14 articles (08/2008 - 02/2003)|
|2.||Charo, Israel F: 9 articles (03/2011 - 12/2002)|
|3.||Egashira, Kensuke: 7 articles (03/2011 - 04/2004)|
|4.||Ahuja, Seema S: 6 articles (09/2011 - 11/2003)|
|5.||Mack, Matthias: 6 articles (09/2010 - 06/2003)|
|6.||Mukaida, Naofumi: 6 articles (10/2009 - 11/2002)|
|7.||Rollins, Barrett J: 6 articles (11/2004 - 12/2002)|
|8.||Quinones, Marlon P: 4 articles (09/2011 - 11/2003)|
|9.||Jimenez, Fabio: 4 articles (09/2011 - 11/2003)|
|10.||White, Fletcher A: 4 articles (08/2009 - 10/2008)|
|1.||Asthma (Bronchial Asthma)
03/01/2010 - "The previous association of the CCR532 deletion with protection from childhood asthma appears to be explained by linkage disequilibrium with the -G190A mutation in the CCR2 receptor gene."
08/01/2007 - "Potent and selective CC-chemokine receptor-2 (CCR2) antagonists as a potential treatment for asthma."
02/01/2007 - "Association between a genetic variation of CC chemokine receptor-2 and atopic asthma."
12/01/2008 - "We identified associations between the V-64I CCR2 polymorphism and protection against asthma, higher FEV1, and absence of BHR in families at high risk of asthma and atopy, suggesting an important role for the CCR2 receptor in modulating airway inflammation independent of atopy."
08/01/2011 - "This application discloses a series of di- and tri-substituted cyclohexanes as CCR2 receptor antagonists which are stated to be useful in treating inflammation and autoimmune diseases, such as type 2 diabetes and asthma. "
12/15/2007 - "Interestingly, the chemokine receptor CCR2 was found to be up-regulated in MSC exposed to irradiated tumor cells and inhibition of CCR2 led to a marked decrease of MSC migration in vitro. "
01/15/2014 - "We identified CCL2 as the major chemokine attracting MDSCs to tumor, whose expression was Tgfbr2-dependent, whereas its receptor CCR2 was highly expressed in MDSC population. "
06/01/2013 - "Recruitment of inflammatory monocytes to the tumor site is mediated by C-C chemokine ligand 2 (CCL2) through binding to its receptor CCR2. "
02/01/2013 - "Inhibition of CCL2 signaling and absence of its cognate receptor CCR2 reduced CD11b/Gr1(mid) recruitment and decreased tumor burden. "
11/01/2012 - "MDSCs from SCCs expressed the chemokine receptor CCR2 (chemokine (C-C motif) receptor 2) and tumors expressed the CCR2 ligand human β-defensin 3 (HBD3), suggesting that CCR2/HBD3 interactions may contribute to MDSC recruitment to SCCs. "
05/15/2011 - "We evaluated the antiinflammatory and epithelial-protective effects of exudate macrophages in a model of LPS- and Klebsiella pneumoniae-induced lung injury comparing wild-type and CC-chemokine receptor 2 (CCR2)-deficient mice with defective lung macrophage recruitment and in in vitro studies using primary alveolar epithelial cells. "
02/01/2004 - "Post-BMT lung injury occurs independently of the expression of CCL2 or its receptor, CCR2, on host cells."
07/01/2005 - "Gene profiling of harvested mast cells also showed increased transcript copy numbers for TNFalpha and CC chemokine receptor 2, which play critical roles in lung injury. "
12/01/2014 - "Monocytes are mainly recruited via their receptor CCR2 and aggravate inflammation. "
12/01/2014 - "CCL2, a major ligand for the chemokine receptor CCR2, is an inflammation-associated chemokine that induces the recruitment of immune cells in tissues. "
01/01/2014 - "Their precursors, for example monocytes, can be recruited to sites of inflammation by the chemokine receptor CCR2, and this has been proposed to be important in AMD. "
01/01/2014 - "We sought to evaluate the role of CC-chemokine receptor 2 (CCR2) in PM2.5-mediated inflammation and IR. "
08/01/2013 - "The chemokine receptor CCR2 controls the release of Ly6C(high) monocytes from the bone marrow and their recruitment to sites of inflammation. "
08/01/2009 - "Expression of the chemokine receptor CCR2 can be detrimental or beneficial for infection resolution. "
04/15/2012 - "Astrocytes produce high levels of CCL2 upon SIV infection, which binds to CCR2 receptors on macrophages, leading to a selective suppression of IFN-α and the IFN-stimulated gene TRAIL while simultaneously inducing IFN-β and MxA. "
07/01/2011 - "Monocytes are mobilized to sites of infection via interaction between the chemokine MCP-1 and its receptor, CCR2, at which point they differentiate into macrophages that mediate potent antimicrobial effects. "
11/11/2010 - "Role of MCP-1 and its receptor CCR2 in monocyte recruitment during infection or under other inflammatory conditions is well known. "
12/24/2009 - "During Plasmodium chabaudi infection in mice, a population of CD11b(high)Ly6C(+) monocytes are generated in bone marrow, most of which depend on the chemokine receptor CCR2 for migration from bone marrow to the spleen. "
|1.||Chemokine CCL2 (Monocyte Chemoattractant Protein 1)
|2.||Immunoglobulin E (IgE)
|4.||Interleukin-8 (Interleukin 8)
|6.||CCR5 Receptors (CCR5 Receptor)
|7.||CD40 Ligand (CD40L)
|9.||Antigen Receptors (Antigen Receptor)
|10.||GTP-Binding Proteins (G-Protein)
|2.||Heart Transplantation (Grafting, Heart)