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Agouti-Related Protein

A secreted protein of approximately 131 amino acids that is related to AGOUTI SIGNALING PROTEIN and is also an antagonist of MELANOCORTIN RECEPTOR activity. It is expressed primarily in the HYPOTHALAMUS and the ADRENAL GLAND. As a paracrine signaling molecule, AGRP is known to regulate food intake and body weight. Elevated AGRP has been associated with OBESITY.
Also Known As:
AGRP Protein; AGRT Protein; Agouti Related Protein
Networked: 146 relevant articles (1 outcomes, 12 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Palmiter, Richard D: 6 articles (09/2013 - 10/2005)
2. Wu, Qi: 5 articles (09/2013 - 02/2008)
3. Nogueiras, Rubén: 4 articles (06/2012 - 08/2010)
4. López, Miguel: 4 articles (06/2012 - 08/2010)
5. Diéguez, Carlos: 4 articles (06/2012 - 08/2010)
6. Luquet, Serge: 3 articles (10/2014 - 10/2005)
7. Miao, Zheng: 3 articles (02/2013 - 02/2010)
8. Liu, Hongguang: 3 articles (02/2013 - 02/2010)
9. Cochran, Jennifer R: 3 articles (02/2013 - 02/2010)
10. Cheng, Zhen: 3 articles (02/2013 - 02/2010)

Related Diseases

1. Body Weight (Weight, Body)
2. Obesity
3. AIDS-Related Complex (ARC)
4. Starvation
5. Small Cell Lung Carcinoma (Small Cell Lung Cancer)

Related Drugs and Biologics

1. Complementary DNA (cDNA)
2. Leptin
3. Neuropeptide Y
4. Type 4 Melanocortin Receptor (Melanocortin-4 Receptor)
5. Pro-Opiomelanocortin (Proopiomelanocortin)
6. Messenger RNA (mRNA)
7. Ghrelin
8. Neuropeptides
9. alpha-MSH
10. Hormones

Related Therapies and Procedures

1. Spinal Injections