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HIV Reverse Transcriptase

A reverse transcriptase encoded by the POL GENE of HIV. It is a heterodimer of 66 kDa and 51 kDa subunits that are derived from a common precursor protein. The heterodimer also includes an RNAse H activity (RIBONUCLEASE H, HUMAN IMMUNODEFICIENCY VIRUS) that plays an essential role the viral replication process.
Also Known As:
Reverse Transcriptase, HIV; Reverse Transcriptase, Human Immunodeficiency Virus; Transcriptase, HIV Reverse
Networked: 65 relevant articles (3 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Ng, T B: 4 articles (02/2009 - 03/2000)
2. Ye, X Y: 3 articles (04/2001 - 03/2000)
3. Lifson, Jeffrey D: 2 articles (09/2012 - 01/2008)
4. Piatak, Michael: 2 articles (09/2012 - 01/2008)
5. Gettie, Agegnehu: 2 articles (09/2012 - 01/2008)
6. Robbiani, Melissa: 2 articles (09/2012 - 01/2008)
7. Blanchard, James: 2 articles (09/2012 - 01/2008)
8. Aravantinou, Meropi: 2 articles (09/2012 - 01/2008)
9. Kenney, Jessica: 2 articles (09/2012 - 01/2008)
10. Douglas, Steven D: 2 articles (11/2010 - 03/2007)

Related Diseases

1. HIV Infections (HIV Infection)
2. AIDS-Related Complex (ARC)
3. Infection
4. Acquired Immunodeficiency Syndrome (AIDS)
5. Neoplasms (Cancer)

Related Drugs and Biologics

1. HIV Protease
2. Lamivudine (3TC)
3. calanolide A
4. Zidovudine (Retrovir)
5. Protease Inhibitors (Protease Inhibitor)
6. Glycoside Hydrolases (Endoglycosidases)
7. tenofovir disoproxil (Viread)
8. HIV Fusion Inhibitors
9. Enzymes
10. DNA-Directed DNA Polymerase (Polymerases, DNA)

Related Therapies and Procedures

1. Highly Active Antiretroviral Therapy (HAART)
2. Drug Therapy (Chemotherapy)