HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Microsatellite Instability

The occurrence of highly polymorphic mono- and dinucleotide MICROSATELLITE REPEATS in somatic cells. It is a form of genome instability associated with defects in DNA MISMATCH REPAIR.
Also Known As:
Replication Error Phenotype; Error Phenotype, Replication; Error Phenotypes, Replication; Instability, Microsatellite; Phenotype, Replication Error; Phenotypes, Replication Error; Replication Error Phenotypes
Networked: 4409 relevant articles (195 outcomes, 410 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Neoplasms (Cancer)
2. Colorectal Neoplasms (Colorectal Cancer)
3. Colonic Neoplasms (Colon Cancer)
4. Stomach Neoplasms (Stomach Cancer)
5. Turcot syndrome

Experts

1. Ogino, Shuji: 73 articles (01/2022 - 01/2006)
2. Fuchs, Charles S: 67 articles (06/2021 - 01/2006)
3. Nosho, Katsuhiko: 42 articles (01/2019 - 07/2007)
4. Chan, Andrew T: 38 articles (01/2022 - 08/2009)
5. Meyerhardt, Jeffrey A: 36 articles (10/2022 - 01/2006)
6. Goel, Ajay: 31 articles (01/2021 - 01/2003)
7. Kim, Kyoung-Mee: 29 articles (05/2022 - 01/2002)
8. Nishihara, Reiko: 29 articles (08/2020 - 06/2012)
9. Kang, Gyeong Hoon: 28 articles (03/2022 - 02/2002)
10. Boland, C Richard: 28 articles (03/2017 - 07/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Microsatellite Instability:
1. Immune Checkpoint InhibitorsIBA
2. pembrolizumabIBA
3. Biomarkers (Surrogate Marker)IBA
4. Fluorouracil (Carac)FDA LinkGeneric
5. Proteins (Proteins, Gene)FDA Link
6. DNA (Deoxyribonucleic Acid)IBA
7. NivolumabIBA
8. LigandsIBA
9. AntibodiesIBA
10. B7-H1 AntigenIBA

Therapies and Procedures

1. Immunotherapy
2. Drug Therapy (Chemotherapy)
3. Therapeutics
4. Adjuvant Chemotherapy
5. Radiotherapy