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Transforming Growth Factor beta2

A TGF-beta subtype that was originally identified as a GLIOBLASTOMA-derived factor which inhibits the antigen-dependent growth of both helper and CYTOTOXIC T LYMPHOCYTES. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta2 and TGF-beta2 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.
Also Known As:
BSC-1 Cell Growth Inhibitor; Cartilage-Inducing Factor-B; Glioblastoma-Derived T-Cell Suppressor Factor; Polyergin; Suppressor Factor, T-Cell, Glioblastoma-Derived; TGF-beta-2; TGF-beta2 Latency-Associated Protein; TGF-beta2LAP; Transforming Growth Factor beta 2 Latency Associated Peptide; BSC 1 Cell Growth Inhibitor; Cartilage Inducing Factor B; Glioblastoma Derived T Cell Suppressor Factor; Latency-Associated Protein, TGF-beta2; TGF beta2 Latency Associated Protein; TGF beta2LAP; TGF-beta2
Networked: 307 relevant articles (9 outcomes, 38 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Bogdahn, Ulrich: 8 articles (10/2014 - 02/2006)
2. Hau, Peter: 7 articles (10/2014 - 02/2006)
3. Jachimczak, Piotr: 4 articles (12/2011 - 02/2006)
4. Weller, M: 4 articles (07/2009 - 06/2001)
5. Fuchshofer, Rudolf: 4 articles (12/2008 - 11/2004)
6. Lane, K B: 4 articles (08/2003 - 03/2001)
7. Light, R W: 4 articles (08/2003 - 03/2001)
8. Thompson, P J: 4 articles (08/2003 - 03/2001)
9. Leukel, Petra: 3 articles (10/2014 - 08/2009)
10. Bosserhoff, Anja-Katrin: 3 articles (01/2013 - 01/2005)

Related Diseases

1. Glioma (Gliomas)
2. Glaucoma
3. Cataract (Cataracts)
4. Ischemia
5. Hypersensitivity (Allergy)

Related Drugs and Biologics

1. Transforming Growth Factor beta1 (TGF beta 1)
2. Transforming Growth Factor beta3 (TGF beta 3)
3. Proteins (Proteins, Gene)
4. Trabedersen
5. Intercellular Signaling Peptides and Proteins (Growth Factors)
6. Transforming Growth Factor beta Receptors (TGF beta Receptors)
7. Connective Tissue Growth Factor
8. Fibrin Tissue Adhesive (Fibrin Sealant)
9. Transforming Growth Factor beta (TGF-beta)
10. Protein Isoforms (Isoforms)

Related Therapies and Procedures

1. Immunotherapy
2. Therapeutics
3. Filtering Surgery
4. Sutures (Suture)
5. Photopheresis