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Interleukin-12 Subunit p35

A subunit of interleukin-12. It binds to the INTERLEUKIN-12 SUBUNIT P40 via a disulfide bond that results in the active cytokine.
Also Known As:
IL-12p35; Interleukin 12a; Interleukin-12 p35; Interleukin 12 Subunit p35; Interleukin 12 p35; Subunit p35, Interleukin-12
Networked: 105 relevant articles (6 outcomes, 15 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Feng, Lin: 9 articles (02/2020 - 07/2017)
2. Jiang, Wei-Dan: 9 articles (02/2020 - 07/2017)
3. Liu, Yang: 9 articles (02/2020 - 07/2017)
4. Wu, Pei: 9 articles (02/2020 - 07/2017)
5. Zhou, Xiao-Qiu: 9 articles (02/2020 - 07/2017)
6. Jiang, Jun: 8 articles (02/2020 - 07/2017)
7. Kuang, Sheng-Yao: 8 articles (02/2020 - 07/2017)
8. Tang, Ling: 8 articles (02/2020 - 07/2017)
9. Ghiasi, Homayon: 5 articles (05/2017 - 06/2002)
10. Ji, Qingwei: 4 articles (01/2020 - 09/2018)

Related Diseases

1. Infections
2. Atherosclerosis
3. Autoimmune Diseases (Autoimmune Disease)
4. Neuroinflammatory Diseases
5. Weight Gain
07/01/2017 - "The results indicated that optimal SB supplementation improved the fish growth performance (percent weight gain, specific growth rate, feed intake and feed efficiency) and intestinal growth and function (intestine weight, intestine length, intestinal somatic index, folds height, trypsin, chymotrypsin, lipase and amylase activities), increased beneficial bacteria lactobacillus amount and butyrate concentration, decreased baneful bacteria Aeromonas and Escherichia coli amounts, reduced acetate and propionate concentrations, elevated lysozyme and acid phosphatase activities, increased complement (C3 and C4) and immunoglobulin M contents, and up-regulated β-defensin-1 (rather than DI), hepcidin, liver expressed antimicrobial peptide 2B (LEAP-2B) (except LEAP-2A), Mucin2, interleukin 10 (IL-10), IL-11 (rather than PI), transforming growth factor β1 (rather than PI), transforming growth factor β2 (rather than PI), IL-4/13A, IL-4/13B and inhibitor of κBα (IκBα) mRNA levels, whereas it down-regulated tumor necrosis factor α, interferon γ2, IL-1β (rather than PI), IL-6, IL-8, IL-15 (rather than PI), IL-17D (rather than PI), IL-12p35, IL-12p40 (rather than PI or MI), nuclear factor kappa B p65 (NF-κB p65) (except NF-κB p52), c-Rel (rather than PI or MI), IκB kinase β (IKKβ) (rather than PI), IKKγ (except IKKα), p38 mitogen-activated protein kinase (p38MAPK) and MAPK kinase 6 mRNA levels in three intestinal segments of young grass carp (P < 0.05), suggesting that SB supplementation improves growth and intestinal immune function of fish. "

Related Drugs and Biologics

1. Interleukin-10 (Interleukin 10)
2. Interleukin-12 Subunit p40
3. Messenger RNA (mRNA)
4. Cytokines
5. Interleukin-6 (Interleukin 6)
6. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
7. Interleukin-8 (Interleukin 8)
8. Interleukin-15 (Interleukin 15)
9. Transforming Growth Factors (Transforming Growth Factor)
10. Apolipoproteins E (ApoE)

Related Therapies and Procedures

1. Immunotherapy
2. Therapeutics