Interleukin-18 Receptor alpha Subunit

A subunit of the interleukin-18 receptor that is responsible of extracellular binding of IL-18.

Also Known As:

CDw218a Antigen; IL1 Receptor-Related Protein; Interleukin 18 Receptor 1; Interleukin-18 Receptor alpha Chain; Antigen, CDw218a; IL1 Receptor Related Protein; Interleukin 18 Receptor alpha Chain; Interleukin 18 Receptor alpha Subunit; Antigens, CDw218a; CDw218a Antigens

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Cell Surface Receptors: 2125
      - Immunologic Receptors: 9
        Cytokine Receptors: 1620
        Interleukin Receptors: 114
        Interleukin-18 Receptors: 95
        Interleukin-18 Receptor alpha Subunit: 7
        human IL18R1 protein
        mouse Il18r1 protein

Experts

1.	An, Huiru: 1 article (01/2014)
2.	Ding, Wenjun: 1 article (01/2014)
3.	Liang, Yan: 1 article (01/2014)
4.	Wu, Xueqiong: 1 article (01/2014)
5.	Yang, Yourong: 1 article (01/2014)
6.	Zhang, Junxian: 1 article (01/2014)
7.	Zhao, Weiguo: 1 article (01/2014)
8.	Zheng, Li: 1 article (01/2014)
9.	Zhu, Donglin: 1 article (01/2014)
10.	Beyeen, Amennai D: 1 article (09/2010)

Related Diseases

1.	Asthma (Bronchial Asthma) 09/01/2008 - "Interleukin 18 receptor 1 gene polymorphisms are associated with asthma." 09/01/2010 - "Gene-based analyses that included all available SNPs in each gene found associations (P < .05) with both phenotypes for several genes: neuronal growth regulator 1 (NEGR1); roundabout, axon guidance receptor, homolog 1 (ROBO1); diacylglycerol kinase, gamma (DGKG); Fas apoptotic inhibitory molecule 2 (FAIM2); fat mass and obesity associated (FTO); and carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 (CHST8) among the BMI GWAS genes; interleukin 1 receptor-like 1 / interleukin 18 receptor 1 (IL1RL1/IL18R1), dipeptidyl-peptidase 10 (DPP10), phosphodiesterase 4D (PDE4D), V-myb myeloblastosis viral oncogene homolog (MYB), PDE10A, IL33, and especially protein tyrosine phosphatase, receptor type D (PTPRD) among the asthma GWAS genes; and protein kinase C, alpha (PRKCA) among the BMI and asthma candidate genes. "
2.	Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune) 04/01/2010 - "[Expression of interleukin-18 and interleukin-18 receptor alpha chain of the peripheral white blood cells in immune thrombocytopenia]."
3.	Tuberculosis (Tuberculoses) 01/01/2014 - "Polymorphisms in the interleukin 18 receptor 1 gene and tuberculosis susceptibility among Chinese."
4.	Sarcoidosis (Schaumann Disease) 10/01/2005 - "To investigate the expression of interleukin-18 receptor alpha chain (IL-18Ralpha) in BAL and peripheral blood (PB) T cells in patients with sarcoidosis compared with control subjects, to evaluate the relationship between the expression and clinical manifestations, and to clarify the mechanisms of altered expression. " 10/01/2005 - "Enhanced expression of interleukin-18 receptor alpha chain by CD4+ T cells in sarcoidosis."
5.	Obesity 09/01/2010 - "Gene-based analyses that included all available SNPs in each gene found associations (P < .05) with both phenotypes for several genes: neuronal growth regulator 1 (NEGR1); roundabout, axon guidance receptor, homolog 1 (ROBO1); diacylglycerol kinase, gamma (DGKG); Fas apoptotic inhibitory molecule 2 (FAIM2); fat mass and obesity associated (FTO); and carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 (CHST8) among the BMI GWAS genes; interleukin 1 receptor-like 1 / interleukin 18 receptor 1 (IL1RL1/IL18R1), dipeptidyl-peptidase 10 (DPP10), phosphodiesterase 4D (PDE4D), V-myb myeloblastosis viral oncogene homolog (MYB), PDE10A, IL33, and especially protein tyrosine phosphatase, receptor type D (PTPRD) among the asthma GWAS genes; and protein kinase C, alpha (PRKCA) among the BMI and asthma candidate genes. "

Related Drugs and Biologics

1.	Type 4 Cyclic Nucleotide Phosphodiesterases
2.	Class 2 Receptor-Like Protein Tyrosine Phosphatases
3.	Protein Kinase C-alpha
4.	Interleukin-18 (Interleukin 18)
5.	Diacylglycerol Kinase
6.	Interleukin-1 Receptors (Interleukin 1 Receptor)
7.	Sulfotransferases
8.	Dipeptidyl-Peptidases and Tripeptidyl-Peptidases
9.	Carbohydrates
10.	Interleukin-33