Interleukin-11 Receptor alpha Subunit

A low affinity interleukin-11 receptor subunit that combines with the CYTOKINE RECEPTOR GP130 to form a high affinity receptor for INTERLEUKIN-11. Multiple isoforms of this protein exist due to ALTERNATIVE SPLICING of its MRNA.

Also Known As:

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Campbell, C L: 1 article (02/2001)
2.	Guardiani, R: 1 article (02/2001)
3.	Nelson, B E: 1 article (02/2001)
4.	Ollari, C: 1 article (02/2001)
5.	Quesenberry, P J: 1 article (02/2001)
6.	Savarese, T M: 1 article (02/2001)

Related Diseases

1.	Ovarian Neoplasms (Ovarian Cancer) 02/01/2001 - "The objectives of this study were to determine (1) the frequency of expression of the interleukin-11 receptor alpha subunit (IL-11Ralpha) and its signal transducing subunit, gp130, among primary ovarian carcinomas; (2) the frequency of expression of IL-11 in ovarian carcinomas; and (3) the potential role IL-11 might have in ovarian cancer cell biology. "
2.	Carcinoma (Carcinomatosis) 02/01/2001 - "The objectives of this study were to determine (1) the frequency of expression of the interleukin-11 receptor alpha subunit (IL-11Ralpha) and its signal transducing subunit, gp130, among primary ovarian carcinomas; (2) the frequency of expression of IL-11 in ovarian carcinomas; and (3) the potential role IL-11 might have in ovarian cancer cell biology. "

Related Drugs and Biologics

1.	Interleukin-11 (Interleukin 11)