|1.||Müller, Werner: 5 articles (05/2014 - 02/2010)|
|2.||Klein, Christoph: 5 articles (11/2013 - 11/2009)|
|3.||Muise, Aleixo M: 4 articles (06/2015 - 01/2013)|
|4.||Grimbacher, Bodo: 4 articles (01/2014 - 11/2009)|
|5.||Boztug, Kaan: 3 articles (03/2015 - 11/2009)|
|6.||Kotlarz, Daniel: 3 articles (11/2013 - 11/2009)|
|7.||Murugan, Dhaarini: 3 articles (11/2013 - 11/2009)|
|8.||Trinchieri, Giorgio: 3 articles (06/2012 - 08/2002)|
|9.||Jack, Robert S: 3 articles (08/2011 - 02/2010)|
|10.||Murray, Henry W: 3 articles (03/2005 - 11/2002)|
11/01/2006 - "Therapeutic administration of an antibody that blocks the IL-10 receptor restored T-cell function and eliminated viral infection. "
02/01/2014 - "In baboon but not macaque cell cultures, SHFV infection upregulated IL-10R1, a subunit of the IL-10 receptor (IL-10R), and also SOCS3, a negative regulator of proinflammatory cytokine production. "
09/01/2009 - "Blockade of the IL-10 receptor or the absence of MyD88 during primary infection restored protective immunity. "
10/01/2007 - "Little information is available on the role of host genetic variation in IL-10 receptor genes and outcome of HCV infection. "
10/30/2006 - "Resolution of a chronic viral infection after interleukin-10 receptor blockade."
|2.||Atopic Dermatitis (Atopic Eczema)
10/01/1999 - "In this study we examined the role of the IL-10 receptor (IL-10R) in the pathophysiology of atopic eczema. "
10/01/1999 - "Differential IL-10 receptor gene expression in acute versus chronic atopic eczema. "
10/01/1999 - "Our results demonstrate for the first time that IL-10 receptors may have a role in the pathogenesis of atopic eczema and its upregulation by FK506 and UVA could explain the therapeutic efficacy of these agents."
10/01/2005 - "Since IL-10 functions through the specific IL-10 receptor alpha (IL-10RA) chain and the IL-10RA gene (Il10ra) is linked to the susceptibility loci of atopic dermatitis and Crohn's disease identified using mouse models, we supposed that IL-10RA might be involved in murine lupus. "
12/01/2013 - "Expression of IL-10 and IL-10 receptor (IL-10R) increased after ischemia. "
07/01/2002 - "Renal ischemia induces the renal production of interleukin 6 and the renal expression of interleukin 10 receptors; interleukin 6 stimulates the production of interleukin 10 by the liver; interleukin 10 ameliorates renal injury. "
06/01/2012 - "Systemic administration of the truncated aptamer was capable of inhibiting tumor growth in mice to an extent comparable to that of an anti- IL-10 receptor antibody."
02/15/1995 - "In vitro analysis of the functional consequences of rhuIL-10 binding to IL-10 receptors on fresh EBV+ tumor cells shows that rhuIL-10 can prevent programmed cell death as well as promote proliferation and can do so at concentrations of huIL-10 found in vivo. "
08/19/2002 - "Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor antibody."
07/15/2012 - "Tumor-resident CD8(+) T cells expressed elevated levels of the IL-10 receptor and were directly activated by IL-10, resulting in prominent phosphorylation of STAT3 and STAT1. "
02/01/2011 - "To neutralize IL-10 in vivo, aiming at cancer therapy, recombinant eukaryotic plasmid expressing the soluble extracellular region of the murine IL-10 receptor α-chain was constructed (pcDNA3-sIL-10R). "
01/01/2012 - "A recent study identified mutations in either IL-10 receptor subunits that are associated with early-onset enterocolitis, a severe phenotype of IBD. "
05/01/2011 - "In "early-onset of enterocolitis (IBD)", a functional IL-10 receptor is lacking. "
10/01/2013 - "Interleukin-10 receptor mutations in children with neonatal-onset Crohn's disease and intractable ulcerating enterocolitis."
03/01/2013 - "Inherited deficiencies of IL-10 or IL-10 receptor (IL-10R) lead to immune dysregulation with life-threatening early-onset enterocolitis. "
06/01/2015 - "Recent advances in genetic diagnosis have identified mutations in gene encoding interleukin-10 (IL-10) and IL-10 receptor (IL-10R) proteins as a cause for early-onset enterocolitis leading to hyperinflammatory immune response. "
|1.||Interleukin-10 (Interleukin 10)
|2.||Interleukin-6 (Interleukin 6)
|4.||Messenger RNA (mRNA)
|7.||Interleukin-8 (Interleukin 8)
|9.||Interferon alpha-beta Receptor (Receptor, Interferon alpha beta)
|10.||Type I Tumor Necrosis Factor Receptors
|4.||Heterologous Transplantation (Xenotransplantation)
|5.||Drug Therapy (Chemotherapy)