Oncostatin M Receptor beta Subunit

An ONCOSTATIN M-specific receptor subunit that combines with CYTOKINE RECEPTOR GP130 to form the ONCOSTATIN M TYPE II RECEPTOR.

Also Known As:

Oncostatin M Receptor beta; Oncostatin M Receptor beta Chain; Receptor, Oncostatin M, beta Subunit

Networked: 12 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Cell Surface Receptors: 2125
      - Immunologic Receptors: 9
        Cytokine Receptors: 1620
        Oncostatin M Receptors: 57
        Type II Oncostatin M Receptors
        Oncostatin M Receptor beta Subunit: 12
        human OSMR protein
        mouse Osmr protein
        rat Osmr protein

Experts

1.	Ralhan, Ranju: 2 articles (06/2011 - 05/2003)
2.	Sharma, Rinu: 2 articles (06/2011 - 05/2003)
3.	Chen, Jing: 1 article (01/2022)
4.	Fan, Zheng: 1 article (01/2022)
5.	Gao, Feng: 1 article (01/2022)
6.	Guo, Tianling: 1 article (01/2022)
7.	Liu, Jingfang: 1 article (01/2022)
8.	Pang, Xuefei: 1 article (01/2022)
9.	Wang, Lixian: 1 article (01/2022)
10.	Xiao, Haixia: 1 article (01/2022)

Related Diseases

1.	Acute-Phase Reaction 04/01/2009 - "In contrast, microarray studies in human renal transplant implantation biopsies indicate a strong acute phase response in the deceased donor kidney, associated with a significant upregulation of oncostatin M receptor beta (OSMR). "
2.	Neoplasms (Cancer) 06/01/2011 - "Expression of oncostatin M receptor beta (OSMRβ) has been reported in human cancers, however its role in esophageal squamous cell carcinoma (ESCC) remains unknown. " 08/01/2015 - "Furthermore IL-31-, IL-31 receptor alpha (IL-31Rα)- and Oncostatin M receptor beta (OSMRβ)-mRNA expression was measured in blood tumor cells from SS patients, memory T-cells from controls and lymphoma cell lines. " 01/01/2022 - "Oncostatin M receptor beta (OSMRβ) mediates signaling of Oncostatin M (OSM) and interleukine-31 (IL-31), two key cytokines involved in many important biological processes including inflammation and cancer progression. "
3.	Melanoma (Melanoma, Malignant) 02/08/2007 - "Loss of oncostatin M receptor beta in metastatic melanoma cells." 05/01/2003 - "Reverse transcription PCR analysis of ESCC and matched normal esophageal tissues provided the first evidence that melanoma metastasis clone D (MEMD), a gene similar to oncostatin M receptor beta, and KIAA0471 gene products are upregulated in ESCCs. "
4.	Inflammation (Inflammations) 08/01/2008 - "When compared with wild-type and IL-6-deficient mice, peritoneal inflammation in oncostatin M receptor-beta-deficient (OSMR-KO) mice resulted in enhanced monocytic cell trafficking. " 08/01/2008 - "Oncostatin M receptor-beta signaling limits monocytic cell recruitment in acute inflammation." 01/01/2022 - "Oncostatin M receptor beta (OSMRβ) mediates signaling of Oncostatin M (OSM) and interleukine-31 (IL-31), two key cytokines involved in many important biological processes including inflammation and cancer progression. "
5.	Primary Cutaneous Amyloidosis 01/01/2014 - "A novel missense mutation in oncostatin M receptor beta causing primary localized cutaneous amyloidosis." 01/01/2008 - "Oncostatin M receptor-beta mutations underlie familial primary localized cutaneous amyloidosis."

Related Drugs and Biologics

1.	Oncostatin M
2.	Cytokines
3.	Messenger RNA (mRNA)
4.	DNA (Deoxyribonucleic Acid)