Leukemia Inhibitory Factor Receptor alpha Subunit (LIF Receptor alpha Subunit)

A receptor subunit that combines with CYTOKINE RECEPTOR GP130 to form the dual specificity receptor for LEUKEMIA INHIBITORY FACTOR and ONCOSTATIN M. The subunit is also a component of the CILIARY NEUROTROPHIC FACTOR RECEPTOR. Both membrane-bound and secreted isoforms of the receptor subunit exist due to ALTERNATIVE SPLICING of its mRNA. The secreted isoform is believed to act as an inhibitory receptor, while the membrane-bound form is a signaling receptor.
Also Known As:
LIF Receptor alpha Subunit; CD118 Antigen; Antigen, CD118; Antigens, CD118; CD118 Antigens
Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results


1. Wu, S: 1 article (01/2001)
2. Liu, H: 1 article (01/2001)
3. Dan, J: 1 article (01/2001)
4. Tang, S: 1 article (01/2001)

Related Diseases

1. Leukemia
2. Acquired Immunodeficiency Syndrome (AIDS)

Related Drugs and Biologics

1. Leukemia Inhibitory Factor
2. Interleukin-6 Receptors (Interleukin 6 Receptor)