Leukemia Inhibitory Factor Receptor alpha Subunit (LIF Receptor alpha Subunit)
A receptor subunit that combines with CYTOKINE RECEPTOR GP130 to form the dual specificity receptor for LEUKEMIA INHIBITORY FACTOR and ONCOSTATIN M. The subunit is also a component of the CILIARY NEUROTROPHIC FACTOR RECEPTOR. Both membrane-bound and secreted isoforms of the receptor subunit exist due to ALTERNATIVE SPLICING of its mRNA. The secreted isoform is believed to act as an inhibitory receptor, while the membrane-bound form is a signaling receptor.
Also Known As:
LIF Receptor alpha Subunit; CD118 Antigen; Antigen, CD118; Antigens, CD118; CD118 Antigens
Networked: 2
relevant articles (0 outcomes,
0 trials/studies)
Bio-Agent Context: Research Results
Experts
1. | Dan, J:
1 article
(01/2001)
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2. | Liu, H:
1 article
(01/2001)
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3. | Tang, S:
1 article
(01/2001)
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4. | Wu, S:
1 article
(01/2001)
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