|1.||Fisher, Paul B: 14 articles (01/2015 - 11/2004)|
|2.||Sarkar, Devanand: 13 articles (01/2015 - 11/2004)|
|3.||Boukerche, Habib: 9 articles (10/2015 - 11/2004)|
|4.||Emdad, Luni: 8 articles (01/2015 - 12/2005)|
|5.||Das, Swadesh K: 8 articles (01/2015 - 01/2012)|
|6.||Dasgupta, Santanu: 7 articles (03/2016 - 01/2012)|
|7.||Pellecchia, Maurizio: 5 articles (01/2015 - 12/2012)|
|8.||Menezes, Mitchell E: 4 articles (01/2015 - 09/2013)|
|9.||Kegelman, Timothy P: 4 articles (01/2015 - 01/2012)|
|10.||Lee, Jeong-Hyung: 4 articles (10/2013 - 06/2002)|
|1.||Neoplasm Metastasis (Metastasis)
01/01/2014 - "In the present study, we aimed to determine the role of MDA-9/Syntenin, a metastasis associated molecule in HNSCC tumorigenesis. "
09/01/2013 - "The present study defines a seminal role of the metastasis-associated gene MDA-9/Syntenin in UCC progression. "
01/15/2013 - "Our studies delineate an unanticipated cell nonautonomous function of MDA-9/syntenin in the context of angiogenesis, which may directly contribute to its metastasis-promoting properties. "
01/01/2014 - "MDA-9/Syntenin overexpression was associated with the stage (p=0.001), grade (p=0.001) and lymph node metastasis (p=0.0001). "
01/01/2014 - "These results suggest that syntenin might contribute to the invasiveness of SCLC and could be utilized as a new therapeutic target for controlling invasion and metastasis in SCLC. "
03/01/2016 - "An appreciable number of studies also established a pivotal role of MDA-9/Syntenin in cancer development and progression. "
01/01/2015 - "Multiple studies demonstrate the importance of MDA-9/Syntenin in tumor invasion and progression. "
01/01/2015 - "Examination of Epigenetic and other Molecular Factors Associated with mda-9/Syntenin Dysregulation in Cancer Through Integrated Analyses of Public Genomic Datasets."
01/01/2015 - "These data confirm that syntenin supports the migration and growth of tumor cells, independently of their origin, and further highlight the attractiveness of syntenin as potential therapeutic target. "
01/01/2015 - "Depending on the cancer model analyzed, syntenin affects various signaling pathways. "
|3.||Melanoma (Melanoma, Malignant)
02/06/2015 - "The present finding uncovers a novel role of MDA-9/syntenin as an important TF·FVIIa·Xa/PAR-1-regulated gene that initiates a signaling circuit essential for cell motility and invasion of metastatic melanoma. "
01/01/2015 - "Melanoma differentiation-associated gene - 9 (MDA-9)/Syntenin has become an increasingly popular focus for investigation in numerous cancertypes. "
01/15/2013 - "Genetic (gain-of-function and loss-of-function) and pharmacologic approaches were used to modify mda-9/syntenin expression in normal immortal melanocytes, early radial growth phase melanoma, and metastatic melanoma cells. "
01/01/2012 - "Melanoma differentiation associated gene-9 (MDA-9), synonymous with syntenin, is an adapter protein that provides a central role in regulating cell-cell and cell-matrix adhesion. "
04/01/2010 - "Although its intracellular form is known as an aggressive melanoma marker, we show for the first time that syntenin was actively secreted and could reduce the invasion process, probably by protein interactions in the B16 model."
|4.||Breast Neoplasms (Breast Cancer)
01/01/2013 - "The present study investigated the expression and function of syntenin in breast cancer. "
01/01/2013 - "We further showed that activation of integrin β1 and ERK1/2 was required for syntenin-mediated migration and invasion of breast cancer cells. "
01/01/2013 - "Overexpression of syntenin in breast cancer cells promoted cell migration and invasion in vitro. "
01/01/2013 - "In addition, the expression level of syntenin in clinical breast cancer tissues was evaluated with immunohistochemistry. "
01/01/2013 - "With a combination of overexpression and RNA interference, the effect of syntenin on migration, invasion, and ERK1/2 activation was examined in breast cancer cell lines. "
|5.||Neurofibromatosis 2 (Neurofibromatosis Type II)
04/01/2003 - "Syntenin, a 33 kDa protein, interacts with several cell membrane receptors and with merlin, the product of the causal gene for neurofibromatosis type II. We report a crystal structure of the functional fragment of human syntenin containing two canonical PDZ domains, as well as binding studies for full-length syntenin, the PDZ tandem, and isolated PDZ domains. "
|1.||Focal Adhesion Protein-Tyrosine Kinases
|2.||Protein Kinases (Protein Kinase)
|3.||Neurofibromin 2 (Merlin)
|6.||Proteins (Proteins, Gene)
|7.||postsynaptic density proteins
|9.||Small Interfering RNA (siRNA)
|10.||Messenger RNA (mRNA)
|1.||Heterologous Transplantation (Xenotransplantation)