|1.||Waldmann, Thomas A: 4 articles (08/2006 - 07/2002)|
|2.||Gershwin, M Eric: 3 articles (05/2010 - 11/2006)|
|3.||Moritoki, Yuki: 3 articles (05/2010 - 11/2006)|
|4.||Ansari, Aftab A: 3 articles (01/2009 - 01/2004)|
|5.||Zhang, Meili: 3 articles (08/2006 - 07/2002)|
|6.||Zhang, Zhuo: 3 articles (08/2006 - 07/2002)|
|7.||Dou, Q Ping: 3 articles (05/2005 - 07/2003)|
|8.||Kuhn, Deborah J: 3 articles (05/2005 - 07/2003)|
|9.||El-Shafey, Eid M: 2 articles (06/2010 - 04/2008)|
|10.||Ueno, Yoshiyuki: 2 articles (05/2010 - 11/2006)|
10/15/2000 - "These results suggest that memory-type CD8(+) T cells play a novel role in the protection against HSV-2 infection in IL-2Ralpha(-/-) mice."
01/01/1997 - "To study immunological responses in filarial infections, interleukin-2 receptor alpha (IL-2R alpha) expression in the peripheral blood lymphocytes (PBL) of Lewis rats infected with Brugia pahangi was observed by flow cytometry. "
05/01/1999 - "The IL-2R induced by the infection consisted mainly of both beta and gamma chains, and the expression of IL-2Ralpha was very low. "
01/01/1994 - "Examination of activation markers on the lymphocyte fraction of afferent lymph revealed a decrease in the number of cells expressing the Interleukin-2 receptor alpha-chain from Day 5 post-infection. "
05/01/1989 - "Infection of fresh mitogen-activated human cord blood and thymocytes yielded immortal T-cell lines that had the same phenotype (CD4+, CD5+, HLA class II+, interleukin 2 receptor alpha-chain +) as lymphocytes transformed by cocultivation with HTLV-I. These experiments demonstrate that the X region encodes the functions of HTLV-I that immortalize a distinct subpopulation of human T cells. "
03/01/2002 - "[Significance of soluble interleukin-2 receptor alpha chain in the management of patients with malignant lymphoma: a multi-center study]."
12/01/2010 - "Levels of soluble interleukin-2 receptor alpha (sIL-2Rα) are known to increase in the sera of patients with certain malignancies, including malignant lymphoma. "
03/01/2002 - "A multi-center series of 117 patients with malignant lymphoma were analyzed to evaluate the clinical significance of soluble interleukin-2 receptor alpha chain (sIL-2R alpha). "
10/01/1993 - "Establishment and characterization of a feline large granular lymphoma cell line expressing interleukin 2 receptor alpha-chain."
08/15/1994 - "Radioimmunotherapy of nude mice bearing a human interleukin 2 receptor alpha-expressing lymphoma utilizing the alpha-emitting radionuclide-conjugated monoclonal antibody 212Bi-anti-Tac."
|3.||Adult T-Cell Leukemia-Lymphoma (Leukemia Lymphoma, T Cell, Acute, HTLV I Associated)
06/01/2012 - "We also identified a soluble form of CADM1 in the peripheral blood of ATLL patients, and the expression levels of this form were correlated with the levels of soluble interleukin 2 receptor alpha. "
12/15/2000 - "IL-2Ralpha-Directed monoclonal antibodies provide effective therapy in a murine model of adult T-cell leukemia by a mechanism other than blockade of IL-2/IL-2Ralpha interaction."
08/01/1994 - "The adult T cell leukemia (ATL)-derived factor (ADF) was first described as an interleukin 2 receptor alpha chain (IL-2R alpha) inducing factor which is produced by an HTLV-I infected cell line. "
03/01/1989 - "Surface and cytoplasmic expression of CD25 antigen in adult T cell leukemia/lymphoma cells have been reported, but similar events concerning CD2 and CD13 antigens have not been described previously. "
07/01/2003 - "We evaluated the efficacy of MEDI-507 (a humanized monoclonal antibody directed against CD2) alone and in combination with humanized anti-Tac (HAT) directed toward CD25, the interleukin-2 receptor alpha (IL-2Ralpha) using a human adult T-cell leukemia xenograft model. "
|4.||Hodgkin Disease (Hodgkin's Disease)
01/01/1996 - "We examined 22 patients in active phase of Hodgkin's disease (HD), 12 patients in complete clinical remission and 16 healthy subjects for their responsiveness to anti-CD3 stimulation as measured by CD25 antigen expression on peripheral blood mononuclear cells (PBMC) and production of CD25-IL-2R alpha. "
06/01/1993 - "Hodgkin and Reed-Sternberg cells, the putative malignant cells of Hodgkin's disease (HD), carry regularly the CD25 antigen that forms one chain of the interleukin-2 (IL-2) receptor (IL-2R alpha). "
06/01/1993 - "The CD25 antigen is expressed by lymphoid populations upon activation and by leukaemias and lymphomas with an activated membrane phenotype (Hodgkin's lymphoma, anaplastic large cell lymphoma, adult T cell leukaemia). "
|5.||Thymoma (Thymic Carcinoma)
04/01/2006 - "Flow cytometric analysis revealed an increasing number of CD3+/CD25+ lymphocytes in the peripheral blood, and the resected thymoma had infiltrated lymphocytes with CD4/CD8/CD25 antigens. "
04/01/2006 - "Hypereosinophilia in a patient with invasive thymoma with clonal T-lymphocyte expansion expressing CD4, CD8, and CD25 antigens."
10/01/2000 - "IL-2Ralpha and HLA-DR were expressed in the medulla at higher frequencies as compared with OX40 in controls as well as MG. In contrast, the numbers of OX40+ cells around the germinal centers (GC) were significantly greater than those of control thymuses, and some mononuclear cells in GC were OX40L+. A considerable number of OX40+ cells were seen in the thymic tissues adjacent to thymomas. "
10/01/2000 - "(The coexpression of OX40 and IL-2Ralpha on activated CD4+ T cells was previously reported.) OX40, expressed in a fraction of activated CD4+ T cells, may be upregulated in thymic tissues adjacent to GC and thymoma in MG, and OX40 may interact with OX40L in GC to enhance anti-acetylcholine receptor antibody production in MG."
|1.||HLA-DR Antigens (HLA-DR)
|5.||Interleukin-2 Receptor alpha Subunit
|6.||Interferon-gamma (Interferon, gamma)
|8.||Interleukin-6 (Interleukin 6)
|9.||Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)
|10.||T-Cell Antigen Receptors (T-Cell Receptor)
|1.||Heterologous Transplantation (Xenotransplantation)
|4.||Homologous Transplantation (Allograft)
|5.||Continuous Ambulatory Peritoneal Dialysis (CAPD)