|1.||Ito, Mamoru: 3 articles (06/2014 - 02/2005)|
|2.||Shultz, Leonard D: 2 articles (12/2009 - 01/2009)|
|3.||Hsu, Amy P: 1 article (07/2015)|
|4.||Freeman, Alexandra F: 1 article (07/2015)|
|5.||Puck, Jennifer M: 1 article (07/2015)|
|6.||Pittaluga, Stefania: 1 article (07/2015)|
|7.||Raffeld, Mark: 1 article (07/2015)|
|8.||Holland, Steven M: 1 article (07/2015)|
|9.||Martinez, Bianca: 1 article (07/2015)|
|10.||Uzel, Gulbu: 1 article (07/2015)|
|1.||Nasal Polyps (Nasal Polyp)
12/01/2009 - "The use of innate and adaptive immunodeficient NOD-scid mice homozygous for targeted mutations in the interleukin-2 receptor gamma-chain locus NOD-scid IL2rgamma(null) for establishing xenografts of nondisrupted pieces of human nasal polyp tissues represents a significant improvement over the previously reported xenograft model that used partially immunoincompetent CB17-scid mice as tissue recipients. "
|2.||Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome)
01/01/2007 - "In this study, we constructed humanized nonobese diabetic/severe combined immunodeficiency (NOD/SCID)/interleukin-2 receptor gamma-chain knockout (IL2Rgamma(null)) (hNOG) mice by transplanting human cord blood-derived hematopoietic stem cells that eventually developed into human B cells, T cells, and other monocytes/macrophages and 4 dendritic cells associated with the generation of lymphoid follicle-like structures in lymphoid tissues. "
07/01/2015 - "Severe combined immunodeficiency (SCID) is most frequently caused by mutations in the cytokine receptor common gamma chain, CD132, encoded by the X-linked gene, IL2RG. "
06/01/2014 - "To prepare the relatively human bone marrow environment in mice, we generated nonobese diabetic/severe combined immunodeficiency/interleukin-2 receptor gamma chain null (NOG) mice expressing human Jagged1 (hJ1) in an osteoblast-specific manner (hJ1-NOG mice) to examine whether Notch signaling induced by hJ1 mediates hHSC proliferation and/or maintenance in mice. "
12/01/1996 - "Interleukin-2 receptor gamma-chain mutations in severe combined immunodeficiency with B-lymphocytes."
09/27/1994 - "Defective human interleukin 2 receptor gamma chain in an atypical X chromosome-linked severe combined immunodeficiency with peripheral T cells."
|3.||X-Linked Combined Immunodeficiency Diseases (X Linked Severe Combined Immunodeficiency)
07/22/2010 - "We reviewed long-term outcomes after gene therapy in nine patients with X-linked severe combined immunodeficiency (SCID-X1), which is characterized by the absence of the cytokine receptor common gamma chain. "
11/15/2008 - "X-linked severe combined immunodeficiency is a life-threatening disorder caused by mutations in the gene encoding the interleukin-2 receptor gamma chain (IL2RG). "
11/01/2008 - "Interleukin-2 receptor gamma chain mutation results in X-linked severe combined immunodeficiency in humans. "
01/01/1997 - "X-linked severe combined immunodeficiency disease (SCID) results from mutations of IL2RG, the gene encoding the interleukin-2 receptor gamma chain, also known as the common gamma chain (gamma c). "
01/01/1997 - "Maternal mosaicism for a novel interleukin-2 receptor gamma-chain mutation causing X-linked severe combined immunodeficiency in a Navajo kindred."
02/01/2005 - "We established human peripheral blood mononuclear cell (PBMC)-transplanted R5 human immunodeficiency virus type 1 isolate JR-FL (HIV-1(JR-FL))-infected, nonobese diabetic-SCID, interleukin 2 receptor gamma-chain-knocked-out (NOG) mice, in which massive and systemic HIV-1 infection occurred. "
01/01/2009 - "We sought to establish an animal model for dengue virus (DENV) infection and immunity using non-obese diabetic/severe combined immunodeficiency interleukin-2 receptor gamma-chain knockout (NOD-scid IL2rgamma(null)) mice engrafted with human hematopoietic stem cells. "
12/01/2013 - "Patients with severe combined immunodeficiencies bearing mutations of adenosine deaminase, adenylate kinase 2, interleukin-2 receptor gamma chain, and Janus kinase 3 genes present NKDs and are prone to a broad range of infections. "
|5.||Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL)
01/01/2001 - "Finally, we show that in this xenograft system T-ALL cells recovered from engrafted bone marrow are characterized by upregulated expression of interleukin 2 receptor gamma chain, suggesting that cord blood preconditioning may function in part to increase T-ALL responsiveness to growth factor(s)."
|1.||Cytokine Receptors (Cytokine Receptor)
|3.||X-linked Severe combined immunodeficiency
|4.||Janus Kinase 3
|5.||Interleukin-2 Receptors (IL 2 Receptor)
|8.||4-((4-((3R)-1-butyl-3-((1R)) cyclohexylhy- droxymethyl)- 2,5- dioxo- 1,4,9- triazaspiro(5.5)undec- 9- yl methyl)phenoxy)benzoic acid hydrochloride
|9.||adenylate kinase 2
|1.||Heterologous Transplantation (Xenotransplantation)