Asthenozoospermia

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140 relevant articles (8 outcomes, 20 trials/studies) found for this Disease

Description: A condition in which the percentage of progressively motile sperm is abnormally low. In men, it is defined as <25% rapid motility or <50% progression in a semen sample (World Health Organization, 1992).

Relationship Network

Disease Context: Research Results

Male Urogenital Diseases

Male Genital Diseases

Infertility: 7561

Male Infertility: 1324

Asthenozoospermia: 140

Related Diseases

1.	Oligospermia (Oligozoospermia)
2.	Infertility (Sterility)
3.	Azoospermia
4.	Infection
5.	Hearing Disorders (Hearing Disorder)
11 Diseases and 58 more articles analyzed in the Research Interface, order at left...

Experts

1.	Mantero, Franco: 2 articles (09/2005 - 01/2004)
2.	Balercia, Giancarlo: 2 articles (09/2005 - 01/2004)
3.	Boscaro, Marco: 2 articles (09/2005 - 01/2004)
4.	Elsawy, M M: 1 article (10/2008)
5.	Hussein, T M: 1 article (10/2008)
6.	Elariny, A F: 1 article (10/2008)
7.	Elgarem, Y F: 1 article (10/2008)
8.	Elabd, M M: 1 article (10/2008)
9.	Garolla, A: 1 article (08/2008)
10.	Ferlin, A: 1 article (08/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Asthenozoospermia:

1.	Kallikreins (Kallikrein)IBA 01/01/1985 - "Infertile men with sperm count below 20 X 10(6)/ml had greater improvement in sperm count than men with sperm count over 20 X 10(6)/ml. This study emphasizes that kallikrein is a relatively good drug for restoring sperm motility in idiopathic oligoasthenozoospermia and asthenozoospermia." 01/01/1985 - "A randomised group of 75 men with idiopathic oligoasthenozoospermia and asthenozoospermia were subjected to control study with kallikrein" 01/01/1992 - "An application of Kallikrein in the swim-up preparation resulted in a higher motility in patients with asthenozoospermia, whereas the patients belonging to the group of oligoasthenozoospermia showed a lower progressive motility compared to the control" 01/01/1991 - "While the groups normo-, oligo-, and asthenozoospermia reached a higher fertilizing capacity under Kallikrein-treatment (probability of error 2.5%), a Kallikrein application in case of oligo-asthenozoospermia had no significant influence on fertilizing capacity" 10/13/1989 - "147 patients with isolated asthenozoospermia treated by means of 600 IU kallikrein daily showed a resultant significant elevation (p less than 0.002) in sperm motility only" Get all the results and reference details, order at left...
2.	Tamoxifen FDA LinkGeneric 01/01/1990 - "Because of the good results achieved with tamoxifen in the treatment of oligozoospermia and with kallikrein in the treatment of asthenozoospermia, a randomized study of the combined treatment of oligoasthenozoospermia suggested itself" Get all the results and reference details, order at left...
3.	Clomiphene (Clomifene)FDA LinkGeneric 10/01/2001 - "In those men whose seminal vesicle function improved after clomiphene treatment, a reduction in the prevalence of asthenozoospermia from 50 to 28.6% (z=3.10, p < 0.002) was observed whereas in those whose seminal vesicles did not respond to clomiphene the prevalence of asthenozoospermia was not reduced (z=1.05; p: NS)" 10/01/2001 - "Asthenozoospermia improves with clomiphene treatment if seminal vesicle function improves after treatment." 05/01/1980 - "76 men with idiopathic oligozoospermia mostly in addition to terato-asthenozoospermia, whose FSH level was in the middle or below the middle of the normal range, were treated with 50 mg clomiphene citrate daily for three months" 03/01/1984 - "The effects of TSUMURA HACHIMIJIOHGAN (TJ-7) and TSUMURA NINJINTOH (TJ-32) on patients with the complaint of male sterility due to both or either oligozoospermia or asthenozoospermia were evaluated in comparison with the effects of clomiphene citrate" Get all the results and reference details, order at left...
4.	Ketotifen (Ketotifene)FDA Link 11/01/1986 - "Treatment of idiopathic oligo- and asthenozoospermia by the mast cell blocker Ketotifen leads to a very moderate, but statistical significant improvement of sperm count and sperm motility" 11/01/1986 - "The use of ketotifen, a mast cell blocker, for treatment of oligo- and asthenozoospermia." Get all the results and reference details, order at left...
5.	Male Contraceptive Agents (Male Contraceptives)IBA 09/01/2008 - "Moreover, after switching medication, drug-induced asthenozoospermia was cured more rapidly than oligozoospermia, suggesting that further delineation of such differences may help to elucidate mechanisms of spermatogenesis and might facilitate the development of non-hormonal male contraceptive agents." Get all the results and reference details, order at left...
6.	royal jellyIBA 05/01/2008 - "OBJECTIVE: To evaluate the efficacy of pericoital intravaginal applications of a mixture of Egyptian bee honey and royal jelly (H/RJ) in the midcycle for the treatment of infertility due to asthenozoospermia" Get all the results and reference details, order at left...
7.	Pentoxifylline (Trental)FDA LinkGeneric 11/01/1985 - "Further studies on the effects of pentoxifylline on sperm count and sperm motility in patients with idiopathic oligo-asthenozoospermia." 05/01/1980 - "The aim of this trial was to study the effects on semen of pentoxifylline administered chronically per os to patients with normogonadotropic asthenozoospermia" 01/01/1999 - "Pentoxifylline stimulates various sperm motion parameters and cervical mucus penetrability in patients with asthenozoospermia." 06/01/1991 - "From the above results, it can be concluded that pentoxifylline is a useful drug in the treatment of normogonadotropic asthenozoospermia." 06/01/1991 - "After giving pentoxifylline to patients with asthenozoospermia for 3 months, sperm motility significantly increased, but sperm concentration did not increase" Get all the results and reference details, order at left...
8.	Carnitine (L-Carnitine)FDA LinkGeneric 02/01/2005 - "OBJECTIVE: To clarify the role of carnitine supplementation in idiopathic asthenozoospermia and to look for a rationale for its use in asthenozoospermic patients" 05/01/1994 - "The authors conclude that oral administration of L-carnitine may improve sperm quality at least in patients with idiopathic asthenozoospermia." 05/01/1994 - "L-carnitine in idiopathic asthenozoospermia: a multicenter study" 05/01/1994 - "The aim of the study described here was to evaluate any possible effect of L-carnitine on spermatozoal motility in a group of patients with unexplained asthenozoospermia in four different infertility centres" 09/01/2005 - "Placebo-controlled double-blind randomized trial on the use of L-carnitine, L-acetylcarnitine, or combined L-carnitine and L-acetylcarnitine in men with idiopathic asthenozoospermia." Get all the results and reference details, order at left...
9.	Testosterone (Sustanon)FDA LinkGeneric 08/01/1983 - "A single intratesticular injection of 0.5 cc of 50 mg/ml of an aqueous testosterone suspension was administered to 14 patients with asthenozoospermia" 08/01/1983 - "Treatment of asthenozoospermia by intratesticular testosterone therapy." 10/01/1990 - "The effect of high-dose (240 mg/d) intake of testosterone (T) undecanoate was studied for sperm characteristics, function of the accessory sex glands, and hormonal parameters of men with idiopathic oligozoospermia, asthenozoospermia, or teratozoospermia using a two-phase protocol including a 3-month double-blind period followed by a 3-month open phase" 02/01/1995 - "Kinetic study of pulsatility of gonadotropin and testosterone secretion in normospermic fertile and infertile men with idiopathic oligo-asthenozoospermia]" 10/01/1991 - "In order to study the possible influence of circulating concentrations of estradiol (E2) and testosterone (T) on the spermatogenesis, 43 subjects, 21 to 43 years of age; 16 of them with oligoasthenozoospermia; 16 with "pure" asthenozoospermia, and 11 with normal semen study, were studied" Get all the results and reference details, order at left...
10.	CatalaseIBA 08/01/2007 - "PATIENTS AND METHODS: In the present study, fatty acid composition of spermatozoa and seminal plasma levels of free 15-F(2t)-Isoprostane and catalase were assayed in men with normozoospermia, asthenozoospermia, asthenoteratozoospermia, and oligoasthenoteratozoospermia" 01/01/2007 - "The aim of the present study was to assess seminal plasma levels of total antioxidant capacity (TAC), free 8-Isoprostane and activities of catalase and superoxide dismutase (SOD) in men with asthenozoospermia, asthenoteratozoospermia and oligoasthenoteratozoospermia compared with normozoospermic males" Get all the results and reference details, order at left...
122 Drugs and Important Bio-Agents and 136 more articles analyzed in the Research Interface, order at left...

Therapies and Procedures

1.	Aftercare (After-Treatment) 01/01/1981 - "They all gave improved findings, which were most unambiguous with regard to the number of spermia.--Findings were at least temporarily normal after treatment in 58 per cent of the patients with asthenozoospermia" 03/01/2003 - "Although no histopathologic lesions or significant changes in the quantitative histologic examination were observed, semen quality examination revealed transient oligospermia (60, 90, 120, and 240mg/kg groups), teratozoospermia (120 and 240mg/kg groups), and asthenozoospermia (240mg/kg group), which returned to normal by the 6th (60 and 90mg/kg groups), 7th (120mg/kg group), or 8th week after treatment (240mg/kg group)" 09/01/1982 - "When comparing semen analyses done before and after treatment with M., a small but distinct reduction of hyperspermia as well as an augmentation of hypospermia were evident, an increase of sperm density in oligozoospermia grade I (20-40 kx 10(6) sperm/ml) was revealed, and an improvement of sperm motility in asthenozoospermia was seen" 10/01/2001 - "Asthenozoospermia improves with clomiphene treatment if seminal vesicle function improves after treatment." 02/01/2000 - "Changes in plasma testosterone and testicular transferrin concentration, testicular histology and semen quality after treatment of testosterone-depot plus PMSG to 3 dogs with asthenozoospermia." Get all the results and reference details, order at left...
2.	Vasectomy (Vas Occlusion) 04/01/1996 - "The mean concentration of S-Tf-R in cases with normozoospermia was 10.4 IU/ml (95% confidence interval: 9.5-11.3) and it was significantly lower in patients with oligozoospermia (6.6, 95% CI: 5.8-7.5, P < 0.001), asthenozoospermia (8.5, 95% CI: 5.5-10.7, P < 0.05), azoospermia of primary testicular origin (7.9, 95% CI: 6.1-9.6, P<0.05) and post-vasectomy samples (5.9, 95% CI: 5.4-6.9, P < 0.001)" 07/01/1995 - "Also the mean (+/- SD) neutral alpha-glucosidase activity in patients with asthenozoospermia (11.7 +/- 9.2) oligozoospermia (11.3 +/- 7.2), and post vasectomy azoospermia (5.3 +/- 3.4) was significantly (p < .05) less than ejaculate from controls (21.2 +/- 14)" Get all the results and reference details, order at left...
3.	Massage (Reflexology) 07/01/1984 - "A similar finding was obtained by comparing the protein spectra of fluid from vesicular massage (EVS), EPS and SP from a man with moderate asthenozoospermia" Get all the results and reference details, order at left...
3 Therapies and Procedures and 8 more articles analyzed in the Research Interface, order at left...

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