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Interleukin-1 Receptor-Associated Kinases

A family of intracellular signaling kinases that were identified by their ability to signal from the activated INTERLEUKIN-1 RECEPTORS. Signaling from these kinases involves their interaction with SIGNAL TRANSDUCING ADAPTOR PROTEINS such as MYELOID DIFFERENTIATION FACTOR 88 and TNF RECEPTOR-ASSOCIATED FACTOR 6.
Also Known As:
IL-1 Receptor-Associated Kinase; IRAK Kinases; IRAK-1 Kinase; IRAK-2 Kinase; IRAK-3 Kinase; IRAK-4 Kinase; Interleukin-1 Receptor-Associated Kinase; Interleukin-1 Receptor-Associated Kinase 1; Interleukin-1 Receptor-Associated Kinase 2; Interleukin-1 Receptor-Associated Kinase 3; Interleukin-1 Receptor-Associated Kinase 4; IL 1 Receptor Associated Kinase; IRAK 1 Kinase; IRAK 2 Kinase; IRAK 3 Kinase; IRAK 4 Kinase; Interleukin 1 Receptor Associated Kinase; Interleukin 1 Receptor Associated Kinase 1; Interleukin 1 Receptor Associated Kinase 2; Interleukin 1 Receptor Associated Kinase 3; Interleukin 1 Receptor Associated Kinase 4; Interleukin 1 Receptor Associated Kinases; Kinase, IL-1 Receptor-Associated; Kinase, IRAK-1; Kinase, IRAK-2; Kinase, IRAK-3; Kinase, IRAK-4; Kinase, Interleukin-1 Receptor-Associated; Kinases, IRAK; Kinases, Interleukin-1 Receptor-Associated; Receptor-Associated Kinase, IL-1; Receptor-Associated Kinase, Interleukin-1; Receptor-Associated Kinases, Interleukin-1
Networked: 108 relevant articles (2 outcomes, 12 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Kobayashi, Koichi S: 5 articles (05/2013 - 10/2010)
2. Flavell, Richard A: 5 articles (06/2012 - 09/2006)
3. Casanova, Jean-Laurent: 3 articles (03/2015 - 04/2004)
4. Li, Liwu: 3 articles (11/2013 - 04/2008)
5. Thomas, James A: 3 articles (04/2009 - 08/2002)
6. Netea, Mihai G: 2 articles (03/2015 - 06/2009)
7. Picard, Capucine: 2 articles (03/2015 - 04/2004)
8. Yan, Mei: 2 articles (01/2015 - 04/2009)
9. von Bernuth, Horst: 2 articles (07/2014 - 02/2008)
10. Schwarz, Klaus: 2 articles (07/2014 - 11/2004)

Related Diseases

1. Infection
2. Pneumonia (Pneumonitis)
3. Sepsis (Septicemia)
4. Necrosis
5. Asthma (Bronchial Asthma)

Related Drugs and Biologics

1. Toll-Like Receptors (Toll-Like Receptor)
2. TNF Receptor-Associated Factor 6 (TRAF6)
3. NF-kappa B (NF-kB)
4. Interleukin-10 (Interleukin 10)
5. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
6. Interferons
7. Transcription Factors (Transcription Factor)
8. Myeloid Differentiation Factor 88
9. Chemokine CCL5
10. Liposomes (Liposome)

Related Therapies and Procedures

1. Injections