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Interleukin-1 Receptor-Associated Kinases

A family of intracellular signaling kinases that were identified by their ability to signal from the activated INTERLEUKIN-1 RECEPTORS. Signaling from these kinases involves their interaction with SIGNAL TRANSDUCING ADAPTOR PROTEINS such as MYELOID DIFFERENTIATION FACTOR 88 and TNF RECEPTOR-ASSOCIATED FACTOR 6.
Also Known As:
IL-1 Receptor-Associated Kinase; IRAK Kinases; IRAK-1 Kinase; IRAK-2 Kinase; IRAK-3 Kinase; IRAK-4 Kinase; Interleukin-1 Receptor-Associated Kinase; Interleukin-1 Receptor-Associated Kinase 1; Interleukin-1 Receptor-Associated Kinase 2; Interleukin-1 Receptor-Associated Kinase 3; Interleukin-1 Receptor-Associated Kinase 4; IL 1 Receptor Associated Kinase; IRAK 1 Kinase; IRAK 2 Kinase; IRAK 3 Kinase; IRAK 4 Kinase; Interleukin 1 Receptor Associated Kinase; Interleukin 1 Receptor Associated Kinase 1; Interleukin 1 Receptor Associated Kinase 2; Interleukin 1 Receptor Associated Kinase 3; Interleukin 1 Receptor Associated Kinase 4; Interleukin 1 Receptor Associated Kinases; Kinase, IL-1 Receptor-Associated; Kinase, IRAK-1; Kinase, IRAK-2; Kinase, IRAK-3; Kinase, IRAK-4; Kinase, Interleukin-1 Receptor-Associated; Kinases, IRAK; Kinases, Interleukin-1 Receptor-Associated; Receptor-Associated Kinase, IL-1; Receptor-Associated Kinase, Interleukin-1; Receptor-Associated Kinases, Interleukin-1
Networked: 261 relevant articles (7 outcomes, 31 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Li, Liwu: 5 articles (01/2017 - 04/2008)
2. Kobayashi, Koichi S: 5 articles (05/2013 - 10/2010)
3. Flavell, Richard A: 5 articles (09/2012 - 09/2006)
4. Chen, Wei: 4 articles (06/2022 - 01/2020)
5. Imaizumi, Masue: 3 articles (01/2021 - 01/2010)
6. Takada, Hidetoshi: 3 articles (01/2021 - 01/2016)
7. Casanova, Jean-Laurent: 3 articles (03/2015 - 04/2004)
8. Thomas, James A: 3 articles (04/2009 - 08/2002)
9. Wei, Tao: 2 articles (06/2022 - 01/2020)
10. Gao, Jun: 2 articles (01/2022 - 08/2020)

Related Diseases

1. Sepsis (Septicemia)
2. Thrombocytopenia (Thrombopenia)
3. Pneumonia (Pneumonitis)
4. Pain (Aches)
5. Staphylococcal Infections

Related Drugs and Biologics

1. Phosphotransferases (Kinase)
2. Lipopolysaccharides
3. 11- (2- pyrrolidin- 1- ylethoxy)- 14,19- dioxa- 5,7,26- triazatetracyclo(19.3.1.1(2,6).1(8,12))heptacosa- 1(25),2(26),3,5,8,10,12(27),16,21,23- decaene
4. Janus Kinases
5. Toll-Like Receptor 2
6. 1- (((2S,3S,4S)- 3- ethyl- 4- fluoro- 5- oxopyrrolidin- 2- yl)methoxy)- 7- methoxyisoquinoline- 6- carboxamide
7. Sulfonic Acids
8. Dinitrobenzenes
9. Sishen Wan
10. Proteins (Proteins, Gene)

Related Therapies and Procedures

1. Therapeutics
2. Punctures
3. Ligation
4. Intravenous Injections
5. Injections