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Interleukin-1 Receptor Accessory Protein

A protein that takes part in the formation of active interleukin-1 receptor complex. It binds specifically to INTERLEUKIN-1 and the INTERLEUKIN-1 RECEPTOR TYPE I at the cell surface to form a heterotrimeric complex that brings its cytoplasmic domain into contact with the cytoplasm domain of the TYPE-I INTERLEUKIN-1 RECEPTOR. Activation of intracellular signal transduction pathways from the receptor is believed to be driven by this form of cytoplasmic interaction.
Also Known As:
IL-1RAcP; Interleukin 1 Receptor Accessory Protein
Networked: 30 relevant articles (1 outcomes, 1 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Humeau, Yann: 2 articles (02/2015 - 01/2010)
2. Sala, Carlo: 2 articles (02/2015 - 01/2010)
3. Chelly, Jamel: 2 articles (02/2015 - 01/2010)
4. Billuart, Pierre: 2 articles (02/2015 - 01/2010)
5. Akoum, Ali: 2 articles (01/2014 - 12/2011)
6. Michaud, Nadège: 2 articles (01/2014 - 12/2011)
7. Joosten, L A B: 2 articles (07/2005 - 10/2003)
8. Arntz, O J: 2 articles (07/2005 - 10/2003)
9. Smeets, R L: 2 articles (07/2005 - 10/2003)
10. van de Loo, F A J: 2 articles (07/2005 - 10/2003)

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