|1.||Hypercalcemia (Milk Alkali Syndrome)
|5.||Bartter Syndrome (Syndrome, Bartter)
|1.||Coe, Fredric L: 18 articles (07/2015 - 03/2002)|
|2.||Pak, Charles Y C: 18 articles (10/2011 - 11/2002)|
|3.||Konrad, Martin: 16 articles (04/2015 - 02/2002)|
|4.||Worcester, Elaine M: 14 articles (07/2015 - 01/2007)|
|5.||Bushinsky, David A: 12 articles (12/2015 - 03/2002)|
|6.||Moe, Orson W: 11 articles (10/2013 - 12/2003)|
|7.||Sakhaee, Khashayar: 11 articles (06/2013 - 11/2002)|
|8.||Thakker, Rajesh V: 9 articles (09/2015 - 04/2003)|
|9.||Bindels, René J M: 9 articles (01/2013 - 12/2003)|
|10.||Evan, Andrew P: 8 articles (07/2015 - 03/2002)|
08/01/1984 - "Low calcium diet combined with hydrochlorthiazide was the most effective treatment for hypercalciuria. "
05/01/2015 - "In a normocalcemic patient with hypercalciuria and a high serum PTH concentration, a thiazide challenge test may help to differentiate SHPT due to a renal calcium leak from normocalcemic PHPT. "
10/01/1978 - "A steep slope of calcium excretion on calcium intake (due to increased calcium absorption) was noted in all hypercalciuric patients and accounted for the significantly improved diagnostic accuracy of screening patients for hypercalciuria on the high-normal calcium intake. "
01/10/2002 - "A low-calcium diet is recommended to prevent recurrent stones in patients with idiopathic hypercalciuria, yet long-term data on the efficacy of a low-calcium diet are lacking. "
11/26/1983 - "Patients with absorptive idiopathic hypercalciuria will be advised to decrease their intake of dairy products as a function of the degree of calcium hyperabsorption, and simultaneously the major dietary sources of oxalate such as chocolate, spinach, rhubarb and asparagus will be eliminated; neutral orthophosphates (3-4 times 500 mg/d) or a thiazide, resp. "
|2.||Hydrochlorothiazide (Esidrix)FDA LinkGeneric
08/01/2011 - "Our results suggest that low dose (0.5 mg/kg/day) of hydrochlorothiazide may be safe and effective in controlling renal hypercalciuria in children."
12/01/2013 - "Since hydrochlorothiazide ameliorates hypercalciuria, we assessed its efficacy in preventing recurrent UTIs in hypercalciuric girls. "
01/01/2012 - "Low-dose or high-dose hydrochlorothiazide in idiopathic hypercalciuria among children? "
08/01/2011 - "To evaluate the therapeutic effect of hydrochlorothiazide in idiopathic renal hypercalciuria. "
07/01/1999 - "After two years on continuous treatment with hydrochlorothiazide, hypercalciuria decreased without deterioration of renal function. "
01/01/2012 - "Similar to other studies in Iran this study shows that the prevalence of hypercalciuria is significantly higher comparing to other countries, it may be associated with excessive intake of sodium."
02/01/1996 - "Children who were normocalciuric at the second study had significantly lower values of urine sodium excretion when compared with those in whom hypercalciuria persisted. "
01/01/2015 - "Urinary sodium was significantly higher in patients with hypercalciuria than without (246.97 ± 103.9 mEq/24 h vs. 200.31 ± 91.6 mEq/24 h, p = 0.001) and hyperuricosuria compared to without (283.24 ± 107.95 mEq/24 h vs. 198.57 ± 85.3 mEq/24 h, p = 0.001). "
04/01/2014 - "Moreover, high sodium excretion was more frequent in men than women (59.2% vs 49.3%, P = .027), whereas hypercalciuria was more common in women (34.5% vs 20.4%, P <.001). "
01/01/2011 - "Dietary intervention for hypercalciuria should include reduced sodium, protein and oxalate intake. "
01/10/2002 - "We conducted a five-year randomized trial comparing the effect of two diets in 120 men with recurrent calcium oxalate stones and hypercalciuria. "
09/01/2000 - "This study defines to what extent hypercalciuria represents a risk factor for recurrent calcium oxalate or nonstruvite stones. "
01/01/2015 - "Calcium oxalate stone growth over sites of Randall's plaque appear to be the primary mode of stone formation for those patients with hypercalciuria. "
10/01/2014 - "Our results showed that rs4142110 was associated with risk of calcium oxalate stone and hypercalciuria (P < 0.05). "
03/01/2011 - "Hypercalciuria was the most frequently found disorder and pyelo-ureteral duplication was the most common anatomical alteration; moreover, calcium oxalate was the most frequent chemical constituent. "
|5.||Vitamin DFDA LinkGeneric
09/01/1989 - "The improvement in hypercalciuria with prostaglandin synthesis inhibition may result in part from correction of this vitamin D abnormality."
10/01/1999 - "Although several studies do not report side effects that may be associated with Ca and vitamin D therapy, the few that do frequently report hypercalciuria. "
09/01/1992 - "Premature infants generally receive substantially more vitamin D than their daily requirements (> 400 IU), but then are no studies on the side effects of high vitamin D intake (hypercalciuria?). "
11/01/2013 - "A 250 μg/week dose of vitamin D was as effective as a 50 μg/d dose in healthy adults, but a regimen of four weekly followed by monthly doses of 1250 μg raised the risk of hypercalciuria."
08/01/2013 - "He had a high 1,25-OH vitamin D level and hypercalciuria. "
04/01/2015 - "We also demonstrate the efficacy of a treatment with thiazides in terms of hypercalciuria in the majority of patients."
11/01/1984 - "[Contribution of thiazides to the study of idiopathic hypercalciuria]."
04/01/2015 - "Treatment with thiazides effectively reduced hypercalciuria in most cases. "
03/01/2012 - "Re: effect of thiazides on bone mineral density in children with idiopathic hypercalciuria."
02/01/2012 - "Effect of thiazides on bone mineral density in children with idiopathic hypercalciuria."
|7.||Alendronate (Alendronate Sodium)FDA LinkGeneric
01/01/2008 - "To establish a clean intermittent self-catheterization programme, the hypercalciuria was treated successfully with alendronate. "
03/01/2007 - "After a median of 9.5 months of treatment, oral alendronate is associated with a lower fracture rate, improvement in BMD and a decrease in hypercalciuria."
04/01/2012 - "Treatment with alendronate reduced hypercalciuria; however, normocalciuria was only obtained with the association of thiazide diuretic. "
09/17/2011 - "[Alendronate and resorptive hypercalciuria]."
01/01/2008 - "Since high-level quadriplegic patients may not be mobilized in the acute phase of the rehabilitation, use of alendronate for preventing hypercalciuria and maintaining a successful clean intermittent self-catheterization programme can be considered as a supportive/complementary measure."
01/01/1997 - "Within the population sample (study 1), 24-hour urinary Na was directly and significantly correlated with prevalence of hypercalciuria when controlling for gender, age, weight, and urinary creatinine: the relationship was continuous and linear for urinary Na ranging between 40 and 200 mmol/24 h. "
01/01/2015 - "Hypercalciuria in FHHt with KLHL3 mutations is less severe than that observed in FHHt with the Q565E WNK4 mutation (0.608 ± 0.196 (n = 10) mmol Ca per mmol creatinine versus 0.860 ± 0.295 (n = 29), respectively (p = 0.0168)). "
04/01/2011 - "Higher transfusion intensity is associated with lower creatinine clearance but more frequent hypercalciuria. "
04/01/2010 - "Compared with Wnk4(+/+) littermate controls, Wnk4(D561A/+) mice manifested hypercalciuria despite no significant differences in serum creatinine, ionized Ca(2+), PTH, and 1,25 hydroxylvitamin D(3) levels. "
10/01/1998 - "All creatinine and electrolyte values were normal for age, and none of the biochemical tests obtained in the children with hypercalciuria was abnormal. "
|9.||Calcitriol (Calcijex)FDA LinkGeneric
01/01/1996 - "Studies in osteoporotic women reveal minimal hypercalciuria with 1 alpha-D2 at doses up to 4 micrograms/day, data suggesting greater safety than reported with calcitriol or 1 alpha-D3. "
09/01/2015 - "Hypercalciuria 12-month incidence (24-h urine Ca >300 mg) was 8.4 (ALN/D5600) versus 13.9 % (calcitriol) (p > 0.05). "
07/01/2010 - "Hypercalciuria was corrected after stopping calcitriol. "
01/01/2007 - "Provided that any attempt to increase the recommended dose of calcitriol was leading to an exacerbation of hypercalciuria, we decided to enroll an alternative tool in the treatment strategy. "
02/19/2004 - "Calcitriol was associated with a higher risk of hypercalciuria. "
|10.||Sodium Chloride Symporter Inhibitors (Diuretics, Thiazide)IBA
03/01/2013 - "It is especially important to consider Cr/kg when there is potential for undertreatment or overtreatment of patients with abnormal Cr/kg. Studies demonstrating hypercalciuria and high Cr/kg may need to be repeated before starting thiazide diuretics. "
08/01/2011 - "Low-dose thiazide diuretics in children with idiopathic renal hypercalciuria."
12/01/2009 - "Thiazide diuretics reduce hypercalciuria in renal tubules, and in addition promote osteoblast differentiation. "
02/05/2009 - "Three, four and eight patients had hypercalciuria at the 4th, 8th and 12th week of treatment, respectively, which were reduced by thiazide diuretics. "
01/01/2006 - "An unusual patient with hypercalciuria and hypomagnesemia unresponsive to thiazide diuretics."
01/01/1992 - "After treatment with thiazide, hypercalciuria was controlled and serum biochemistry normalized. "
04/01/1989 - "Twenty-seven normocalcemic patients aged 11-69 yrs with recurrent renal stone formation and idiopathic hypercalciuria were studied before and after treatment with hydrochlorthiazide (TD) 50 mg twice a day for 6 months. "
04/01/1989 - "Histomorphometric analysis of bone in idiopathic hypercalciuria before and after treatment with thiazide."
07/01/1996 - "Remission of hypercalciuria in patients with tuberculosis after treatment."
01/01/1992 - "After treatment, metabolic acidosis and hypercalciuria improved, and the patient had a catch-up growth phase. "
|2.||Drug Therapy (Chemotherapy)
02/01/2011 - "In terms of pharmacotherapy, there are drugs to successfully improve hypercalciuria, hypocitraturia, aciduria, hyperuricosuria, and hypercystinuria. "
03/01/1996 - "In cases of hypercalciuria it is suitable to prescribe adjuvant specific diets or drug therapy."
12/01/1994 - "Following completion of the chemotherapy, hypercalcaemia and hypercalciuria returned with levels similar to those observed pretreatment. "
05/01/1990 - "Their hypercalciuria was difficult to manage and required frequent manipulations of drug therapy and diet restrictions. "
03/01/1984 - "Pharmacotherapy in children with idiopathic hypercalciuria and symptomatology other than renal stones is controversial and should be limited to patients with severe clinical manifestations."
|3.||Protein-Restricted Diet (Diet, Protein Restricted)
01/01/1999 - "The influence of a low protein diet in idiopathic hypercalciuria."
04/01/1987 - "After the oxalate bolus the positive changes in oxalate excretion were 11.8 +/- 4.8 (low protein) and 17.8 +/- 4.7 (high protein) for controls, and 11.4 +/- 4.4 (low protein) and 31.8 +/- 5.2 (high protein) for patients with absorptive hypercalciuria type II. Thus, the increases in post-load urinary oxalate levels observed for controls and patients were greater on the high protein than on the low protein diets. "
01/01/1960 - "[Low-protein diet as the sole current dietetic means of reducing lithiasic hypercalciuria]."
04/01/1987 - "After the oxalate load the increases in urinary oxalate and calcium oxalate supersaturation were significantly greater for patients with absorptive hypercalciuria type II than for control subjects for the high protein but not the low protein diets (p less than 0.05)."
03/01/1981 - "The phosphorus supplement effectively prevented the hypercalciuria caused by adding the sulfur amino acids to the low protein diet."
|4.||Transplantation (Transplant Recipients)
12/24/1970 - "Transplantation of a kidney from a patient with idiopathic hypercalciuria."
10/01/2007 - "Hypercalciuria induced by a high dose of cinacalcet in a renal-transplant recipient."
10/01/2007 - "Herein, we report on a kidney-transplant recipient with persisting hyperparathyroidism who developed hypercalciuria afterreceiving high doses of cinacalcet. "
06/01/1989 - "Factors predisposing to stone formation included a reconstructive urologic procedure at the time of transplantation (n = 4) or a surgical complication (n = 4), necessitating the placement of a ureteral stent and/or nephrostomy tube, secondary hyperparathyroidism (n = 5), hyperuricosuria (n = 4), and hypercalciuria (n = 1). "
07/01/2011 - "However, given the narrow therapeutic window with respect to hypercalcemia and hypercalciuria, and the demonstrated efficacy of bisphosphonates to prevent post-transplantation bone loss, we regard these agents as adjunctive rather than primary therapy for transplantation osteoporosis. "
|5.||Homologous Transplantation (Allograft)
03/01/1982 - "A 13-year-old boy with primary hyperoxaluria and a successful renal allograft developed symptomatic bone disease, hypercalcemia, and hypercalciuria. "
01/01/2013 - "Interval imaging tracks the new onset of renal allograft stone formation after initiating Cinacalcet up to 60mg daily, which was accompanied by persistent hypercalciuria (478.2 mg/24 hours). "
11/01/2015 - "Teriparatide (recombinant parathyroid hormone) injections were initiated (up to three times daily) with improvement in the vascular changes and a decrease in calcium phosphate calcification in biopsy, as well as reduction in hypercalciuria, restoration of calcium phosphate homeostasis and stabilization of allograft function. "