|1.||Rakin, Ana K: 1 article (08/2007)|
|2.||Ristovski, Jasmina S: 1 article (08/2007)|
|3.||Dimitrijevic, Ljiljana A: 1 article (08/2007)|
|4.||Kustrimović, Natasa Z: 1 article (08/2007)|
|5.||Mileva, Mićić V: 1 article (08/2007)|
|6.||Petrović-Djergović, Danica M: 1 article (08/2007)|
|7.||Lee, Hyun Chul: 1 article (11/2005)|
|8.||Lim, Sung Kil: 1 article (11/2005)|
|9.||Hong, Soon Won: 1 article (11/2005)|
|10.||Ahn, Chul Woo: 1 article (11/2005)|
|1.||Pituitary Neoplasms (Pituitary Adenoma)
11/01/1986 - "Internalization and subcellular distribution of radiolabeled somatostatin-28 in mouse anterior pituitary tumor cells."
07/01/1985 - "Relationship between receptor binding and biopotency of somatostatin-14 and somatostatin-28 in mouse pituitary tumor cells."
08/01/1989 - "Previous studies have shown that somatostatin receptors on AtT-20 and GH3 pituitary tumor cells show relative preference for binding somatostatin-28 (S-28) and somatostatin-14 (S-14), respectively. "
06/24/2005 - "This may explain superior somatostatin-28 potency and provides a rationale for somatostatin ligand design to treat ACTH-secreting pituitary tumors."
07/01/1985 - "Activation of somatostatin-14 (S-14) receptors on mouse AtT-20 pituitary tumor cells by S-14 or somatostatin-28 (S-28) inhibits forskolin-stimulated cAMP synthesis and ACTH secretion. "
07/01/1985 - "The potency of somatostatin-28 (S-28) for regulating these processes in these tumor cells has not been reported. "
04/01/1989 - "Somatostatin receptor content was measured by receptor autoradiography on frozen tumor tissue sections using either a somatostatin-28 analog or a SRIH octapeptide analog (Tyr3-octreotide) as iodinated radioligands. "
01/01/1984 - "Somatostatin-28 and the cyclic hexapeptide analog of somatostatin cyclo(Pro-Phe-D-Trp-Lys-Thr-Phe) failed to influence the growth of this tumor. "
03/12/1998 - "Des-AA1,5-[Tyr2, D-Trp8, IAmp9]somatostatin was found to have a high affinity, comparable to that of the natural somatostatin-28, for sst1-expressing tumors such as prostate cancers. "
08/08/1997 - "Somatostatin-14, somatostatin-28, and prosomatostatin[1-10] are independently and efficiently processed from prosomatostatin in the constitutive secretory pathway in islet somatostatin tumor cells (1027B2)."
05/16/1988 - "The selective binding of somatostatin-28 (SS-28) to beta cells of hamster insulinoma was characterized using HPLC-purified 125I-[Leu8,D-Trp22,Tyr25]SS-28 or 125I-SS-28. "
03/01/1982 - "Saturable and high affinity binding sites have been obtained for an iodinated somatostatin-28 (SS-28) analog, [Leu8,D-Trp22,125I-Tyr25] SS-28, in a membrane preparation from hamster insulinoma, mainly composed of pancreatic beta-cells. "
03/01/2005 - "All insulinomas expressed high-affinity somatostatin receptors of subtype sst2, as shown by receptor autoradiography in vitro using 125I-[tyrosine3]-octreotide and 125I-[leucine8, Dtryptophan22, tyrosine25]-somatostatin-28 with an sst2 subtype-selective analogue. "
08/05/1992 - "Somatostatin-28 (SRIF-28) preferring receptors were solubilized from hamster beta cell insulinoma using the zwitterionic detergent 3-[(3-cholamidopropyl) dimethylammonio]-1-propanesulfonate. "
12/08/1989 - "Somatostatin receptors of plasma membranes from beta cells of hamster insulinoma were covalently labelled with 125I-[Leu8,D-Trp22,Tyr25]somatostatin-28 (125I-somatostatin-28) and solubilized with the non-denaturing detergent Triton X-100. "
|4.||Alzheimer Disease (Alzheimer's Disease)
10/01/2002 - "Interstitial cells subjacent to the entorhinal region expressing somatostatin-28 immunoreactivity are susceptible to development of Alzheimer's disease-related cytoskeletal changes."
08/18/1986 - "The relative proportions of both somatostatin-14 and its precursors somatostatin-28 and the 15 Kdalton prosomatostatin were evaluated by radioimmunoassay in the cerebrospinal fluid of patients with Alzheimer's disease. "
12/01/1995 - "Low cerebrospinal fluid concentrations of peptide histidine valine and somatostatin-28 in Alzheimer's disease: altered processing of prepro-vasoactive intestinal peptide and prepro-somatostatin."
11/01/1982 - "Somatostatin-28 like immunoreactivity was present in pancreatic islets cells and in the epithelial cells of the duodenum as well as in the duodenal somatostatinoma and in pancreatic tumour cells. "
11/01/2005 - "Duodenal somatostatinoma associated with diabetic ketoacidosis presumably caused by somatostatin-28 hypersecretion."
11/01/1982 - "Indirect immunofluorescence techniques using specific antisera against somatostatin-28 were carried out in normal pancreas, duodenum, a somatostatinoma in the duodenum, and pancreatic tumour cells containing somatostatin-14 positive cells, in order to establish if somatostatin-28 is present in normal and pathological tissues. "
|1.||Somatostatin (Somatotropin Release-Inhibiting Factor)
|2.||Somatostatin Receptors (Somatostatin Receptor)
|4.||Adrenocorticotropic Hormone (ACTH)