|1.||Somji, Seema: 3 articles (12/2011 - 04/2008)|
|2.||Zhou, Xu Dong: 3 articles (12/2011 - 04/2008)|
|3.||Sens, Mary Ann: 3 articles (12/2011 - 04/2008)|
|4.||Garrett, Scott H: 3 articles (12/2011 - 04/2008)|
|5.||Sens, Donald A: 3 articles (12/2011 - 04/2008)|
|6.||Cao, Ling: 2 articles (12/2011 - 07/2010)|
|7.||Zheng, Yun: 2 articles (12/2011 - 07/2010)|
|8.||Dunlevy, Jane R: 2 articles (12/2011 - 07/2010)|
|9.||Smith, Frances J D: 2 articles (05/2011 - 03/2008)|
|10.||McLean, W H Irwin: 2 articles (05/2011 - 03/2008)|
|1.||Pachyonychia Congenita (Jadassohn-Lewandowsky Syndrome)
07/01/2015 - "A novel H1 mutation in keratin 6a in an infant with pachyonychia congenita."
01/01/2014 - "Delayed-onset pachyonychia congenita caused by a novel mutation in the V2 domain of keratin 6b."
05/01/2011 - "Pachyonychia congenita (PC) is a keratinizing disorder predominantly caused by mutations in keratin 6a (K6a) (∼50% of cases) or K6b, K16, or K17. "
02/01/2010 - "To identify the mutation in the keratin 6A(K6A) gene in a pedigree with pachyonychia congenita type I (PC-I). "
02/01/2010 - "[The 521 T--> C mutation in the keratin 6A gene in a pedigree with pachyonychia congenita type I]."
12/01/2011 - "The present results, coupled with previous studies, indicate that malignant transformation of UROtsa cells by Cd(+2) or As(+3) produce similar patterns of keratin 6, 7, 16, 17, and 19 in the resulting series of cell lines and their respective tumors."
12/01/2011 - "The expression of keratin 6, 16, and 17 was also correlated with areas of the urothelial tumor cells that had undergone squamous differentiation. "
06/01/2009 - "The GLI1-induced tumors are histologically heterogeneous and involve the expansion of a population of epithelial cells expressing the progenitor cell markers keratin 6 and Bmi-1. "
04/01/2008 - "Immunostaining of keratin 6a in tumor heterotransplants showed focal staining of the tumor cells that was localized to the cytoplasm. "
08/15/2002 - "To test this hypothesis, two transgenic mouse lines were generated that differentially expressed e12S-LOX under the control of the bovine keratin 6 promoter known to be constitutively up-regulated in mouse skin tumors. "
12/01/2015 - "Such cells also express keratin 6, a marker for hyperplasia. "
02/19/1998 - "The epidermis of HK1.bcl-2 mice exhibited multifocal hyperplasia without associated hyperkeratosis and aberrant expression of keratin 6. The rate of proliferation was similar in HK1.bcl-2 and control epidermis although suprabasal BrdUrd incorporating cells were present only in HK1.bcl-2 skin. "
05/01/1997 - "These follicular abnormalities were accentuated by immunohistochemical detection of mouse specific keratin 6, a nonspecific marker of epidermal hyperplasia. "
06/29/1990 - "Expression of the BNLF-1 oncogene of Epstein-Barr virus in the skin of transgenic mice induces hyperplasia and aberrant expression of keratin 6."
05/01/1996 - "This short (2.2-kb) keratin 6 (K6) promoter element was generally silent in untreated animals but was induced in keratinocytes when placed in culture or, in vivo, in response to hyperplasia that follows topical application of the tumor promoter, 12-O-tetradecanoylphorbol-13-acetate. "
|4.||Wounds and Injuries (Trauma)
01/01/2013 - "Moving to a complementary human ex vivo wounded skin assay, we demonstrate that the effects of TRH are conserved across the amphibian-mammalian divide: TRH stimulates wound closure and formation of neo-epidermis in organ-cultured human skin, accompanied by increased keratinocyte proliferation and wound healing-associated differentiation (cytokeratin 6 expression). "
01/01/2006 - "At wound edges in wild-type mice, EPPK was expressed in proliferating keratinocytes in conjunction with keratin 6. In EPPK-/- mice, no similar proliferating keratinocytes were observed, but migrating keratinocytes weakly expressed keratin 6. EPPK was coexpressed with keratin 6 in some keratinocytes in explant cultures from wild mice. "
10/27/2003 - "Loss of keratin 6 (K6) proteins reveals a function for intermediate filaments during wound repair."
11/01/1998 - "We have examined the expression of four Hsps (Hsp27, Hsp60, Hsp70 and Hsp90) and a keratin (keratin 6) by immunohistochemistry during cutaneous wound repair from Day 1 to Day 21 after wounding in the mouse. "
09/01/1997 - "All four transcripts were upregulated in actual healing skin wounds, HB-EGF and keratin 6 being the most prominent. "
|5.||Psoriasis (Pustulosis Palmaris et Plantaris)
02/01/2001 - "Keratin 6 is a marker of hyperproliferative, activated keratinocytes, found in wound healing, psoriasis, and other inflammatory disorders. "
10/01/2006 - "The patchy expression of keratin 6 in the inner margin became homogeneous in the centre of the psoriasis plaque and here was also coexpression of keratin 6 and keratin 10 in a single cell. "
09/08/1995 - "The suprabasal keratin 6 (K6) is remarkable among the keratins as, in addition to being constitutively expressed in different stratified epithelia, it is induced in epidermis under hyperproliferative conditions, such as benign or malignant tumors, psoriasis, and wound healing. "
01/01/2005 - "Treatment of psoriasis with short-term topical steroid resulted towards normalization of Ki-67 antigen, beta-1 integrin, keratin 10 and keratin 6 expression, which are parameters for proliferation and differentiation. "
01/01/2000 - "Changes in keratin 6 and keratin 10 (co-)expression in lesional and symptomless skin of spreading psoriasis."
|1.||Small Interfering RNA (siRNA)
|8.||Messenger RNA (mRNA)
|10.||Keratin-16 (Keratin 16)