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Epidermolytic Palmoplantar Keratoderma

An autosomal dominant hereditary skin disease characterized by epidermolytic hyperkeratosis that is strictly confined to the palms and soles. It has been associated with mutations in the gene that codes for KERATIN-9.
Also Known As:
Keratoderma, Palmoplantar, Epidermolytic; EPPK (Epidermolytic Palmoplantar Keratoderma); Epidermolytic Palmoplantar Keratoderma Vorner Type; Hyperkeratosis, Localized Epidermolytic; Keratoderma, Epidermolytic Palmoplantar; Keratosis of Greither; Palmoplantar Keratoderma, Epidermolytic; Thost-Unna Disease, Epidermolytic; Unna-Thost Disease, Epidermolytic; EPPKs (Epidermolytic Palmoplantar Keratoderma); Epidermolytic Hyperkeratoses, Localized; Epidermolytic Hyperkeratosis, Localized; Epidermolytic Palmoplantar Keratodermas; Epidermolytic Thost-Unna Disease; Epidermolytic Unna-Thost Disease; Greither Keratosis; Hyperkeratoses, Localized Epidermolytic; Keratodermas, Epidermolytic Palmoplantar; Localized Epidermolytic Hyperkeratoses; Localized Epidermolytic Hyperkeratosis; Palmoplantar Keratodermas, Epidermolytic; Thost Unna Disease, Epidermolytic; Unna Thost Disease, Epidermolytic
Networked: 71 relevant articles (0 outcomes, 1 trials/studies)

Disease Context: Research Results

Related Diseases

1. Palmoplantar Keratoderma (Keratosis Palmaris et Plantaris)
2. Epidermolytic Hyperkeratosis (Bullous Congenital Ichthyosiform Erythroderma)
3. Ichthyosis Bullosa of Siemens
4. Pachyonychia Congenita (Jadassohn-Lewandowsky Syndrome)
5. Monilethrix

Experts

1. Chen, Xiao-Ling: 6 articles (09/2018 - 05/2009)
2. Zhang, Xian-Ning: 6 articles (09/2018 - 05/2009)
3. Ke, Hai-Ping: 4 articles (09/2018 - 04/2012)
4. Du, Zhen-Fang: 3 articles (03/2016 - 09/2011)
5. Xu, Chen-Ming: 3 articles (08/2014 - 05/2009)
6. Zhang, X-N: 3 articles (09/2009 - 04/2004)
7. Gao, Xiang: 2 articles (09/2018 - 03/2016)
8. Lin, Zhao-Yu: 2 articles (09/2018 - 03/2016)
9. Luan, Xiao-Rui: 2 articles (09/2018 - 03/2016)
10. Tang, Yue-Xiao: 2 articles (09/2018 - 03/2016)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Epidermolytic Palmoplantar Keratoderma:
1. Type I Keratins (Type I Keratin)IBA
2. Keratin-9 (Keratin 9)IBA
3. Keratins (Keratin)IBA
4. Keratin-1IBA
5. Type II Keratins (Type II Keratin)IBA
6. Aquaporin 5IBA
7. PlakophilinsIBA
8. Small Interfering RNA (siRNA)IBA
9. RNA Splice SitesIBA
10. Aquaporins (Water Channels)IBA

Therapies and Procedures

1. Therapeutics
2. RNAi Therapeutics