Epidermolytic Palmoplantar Keratoderma

An autosomal dominant hereditary skin disease characterized by epidermolytic hyperkeratosis that is strictly confined to the palms and soles. It has been associated with mutations in the gene that codes for KERATIN-9.
Also Known As:
Keratoderma, Palmoplantar, Epidermolytic; EPPK (Epidermolytic Palmoplantar Keratoderma); Keratoderma, Epidermolytic Palmoplantar; Palmoplantar Keratoderma, Epidermolytic; Thost-Unna Disease, Epidermolytic; Unna-Thost Disease, Epidermolytic; EPPKs (Epidermolytic Palmoplantar Keratoderma); Epidermolytic Palmoplantar Keratodermas; Epidermolytic Thost-Unna Disease; Epidermolytic Unna-Thost Disease; Keratodermas, Epidermolytic Palmoplantar; Palmoplantar Keratodermas, Epidermolytic; Thost Unna Disease, Epidermolytic; Unna Thost Disease, Epidermolytic
Networked: 66 relevant articles (0 outcomes, 1 trials/studies) for this Disease, Comments

Disease Context: Research Results

Related Diseases

1. Palmoplantar Keratoderma (Keratosis Palmaris et Plantaris)
2. Epidermolytic Hyperkeratosis (Bullous Congenital Ichthyosiform Erythroderma)
3. Pachyonychia Congenita (Jadassohn-Lewandowsky Syndrome)
4. Ichthyosis Bullosa of Siemens
5. Monilethrix


1. Zhang, Xian-Ning: 3 articles (04/2012 - 05/2009)
2. Chen, Xiao-Ling: 3 articles (04/2012 - 05/2009)
3. Zhang, X-N: 3 articles (09/2009 - 04/2004)
4. Jiang, Miao: 2 articles (02/2014 - 07/2008)
5. Sprecher, E: 2 articles (03/2013 - 01/2013)
6. Lu, Jia-Jun: 2 articles (04/2012 - 09/2011)
7. Liu, Wen-Ting: 2 articles (04/2012 - 09/2011)
8. Xu, Chen-Ming: 2 articles (09/2011 - 05/2009)
9. Chen, Chun-Yue: 2 articles (09/2011 - 05/2009)
10. Christiano, A M: 2 articles (10/2010 - 05/2000)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Epidermolytic Palmoplantar Keratoderma:
1. Type I Keratins (Type I Keratin)IBA
2. Keratin-9 (Keratin 9)IBA
3. Keratins (Keratin)IBA
4. Keratin-1IBA
5. Type II Keratins (Type II Keratin)IBA
6. RNA Splice SitesIBA
7. Leucine (L-Leucine)FDA Link
8. EtretinateFDA Link
9. Hyperkeratosis of the palms and soles and esophageal papillomasIBA
10. Mal de MeledaIBA

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