|1.||Linder, Stig: 11 articles (03/2014 - 03/2004)|
|2.||Ulukaya, Engin: 8 articles (08/2015 - 02/2007)|
|3.||Antoine, Daniel J: 7 articles (03/2015 - 12/2009)|
|4.||Yilmaz, Yusuf: 7 articles (12/2010 - 02/2007)|
|5.||Park, B Kevin: 6 articles (03/2015 - 12/2009)|
|6.||Dive, C: 6 articles (10/2013 - 05/2008)|
|7.||Jenkins, Rosalind E: 5 articles (03/2015 - 12/2009)|
|8.||Feldstein, Ariel E: 5 articles (01/2014 - 11/2008)|
|9.||Omary, M Bishr: 4 articles (12/2015 - 08/2003)|
|10.||Ward, T: 4 articles (05/2012 - 05/2008)|
01/01/2011 - "Cytokeratin 18 (CK18) can be used as a serum biomarker for carcinoma cell death, whereas caspase-cleaved (ccCK18) fragments reflect tumour apoptosis. "
07/01/2009 - "As the molecular forms of cytokeratin 18, either caspase cleaved or not, have been associated with apoptotic or necrotic cell death, respectively, we determined if increases in either or both cytokeratin 18 forms could be observed following IFNalpha protein or Ad-IFN treatment of bladder carcinoma cells. "
01/01/2009 - "The M30-Apoptosense ELISA is a PD biomarker assay for the quantitative determination of caspase-cleaved cytokeratin 18 (CK18) released from apoptotic carcinoma cells into blood. "
11/07/2005 - "To explore the biological behavior of gastric carcinoma micrometastasis (MM) with a marker of cytokeratin 18 (CK18) and to evaluate the clinical stage of gastric carcinoma and its prognosis. "
10/01/2005 - "[High values of soluble cytokeratin 18 in breast carcinomas may have different meanings]."
01/01/2015 - "We reasonably classified as SS patients with US-fatty liver, normal liver function tests (LFTs) and with Cytokeratin 18 <246 mIU/ml. Liver biopsy was performed in 41 patients with US-fatty liver and persistent elevation of LFTs (>6 months). "
01/01/2014 - "We evaluated the usefulness of serum cytokeratin 18 fragment (CK18-F) as a noninvasive biomarker in differentiating nonalcoholic steatohepatitis (NASH) from nonalcoholic fatty liver (NAFL) since the prognosis of the 2 diseases differ. "
01/01/2014 - "Serum Cytokeratin-18 Is Associated with NOX2-Generated Oxidative Stress in Patients with Nonalcoholic Fatty Liver."
10/01/2010 - "Apoptosis in nonalcoholic steatohepatitis with normal aminotransferase values: zooming in on cytokeratin 18 fragments."
04/01/2010 - "Cytokeratin-18 fragments levels were lower in healthy subjects (148 U/L) than patients with simple fatty liver (174 U/L, P=0.013) than patients with nonalcoholic steatohepatitis (355 U/L, P<0.001) offering excellent diagnostic accuracy for differentiation between the 2 latter groups (c-statistic: 0.87). "
05/01/2013 - "Herein, we aimed to study the association between hepatic fat accumulation as assessed by magnetic resonance imaging and circulating levels of cytokeratin-18 (CK-18) fragments, a robust NASH biomarker, and to explore the impact on this association of ethnicity, insulin resistance, and single nucleotide polymorphisms (SNPs) associated with steatosis (rs738409 in the PNPLA3, rs1260326 in the GCKR) or NASH severity (rs2645424 in the FDFT1). "
09/01/2015 - "Moreover, LBP was associated with insulin resistance and dyslipidaemia, and modestly increased with the cytokeratin-18 fragment level but not liver stiffness measurement by transient elastography. "
11/07/2009 - "To elucidate the possible crosstalk between angiogenesis, cytokeratin-18 (CK-18), and insulin resistance (IR) especially in patients with non-alcoholic steatohepatitis (NASH). "
11/07/2009 - "Crosstalk between angiogenesis, cytokeratin-18, and insulin resistance in the progression of non-alcoholic steatohepatitis."
06/01/2015 - "Two indexes were calculated, one combining alanine and aspartate transaminase and cytokeratin 18 and another cytokeratin 18, homeostasis model assessment of insulin resistance and aspartate aminotransferase. "
|4.||Liver Diseases (Liver Disease)
12/01/2011 - "The novel biomarker helpful in identifying and monitoring activity of liver disease may be cytokeratin 18. "
03/01/2014 - "[Cytokeratin 18 as marker for non-invasive diagnosis and prognosis of acute and chronic liver diseases]."
12/01/2011 - "[Cytokeratin 18 as an indicator of the activity of liver disease]."
10/01/2011 - "Cytokeratin 18 (CK18) is a novel serologic biomarker for occupational liver disease. "
12/01/2009 - "Systematic review: caspase-cleaved fragments of cytokeratin 18 - the promises and challenges of a biomarker for chronic liver disease."
|5.||Melanoma (Melanoma, Malignant)
03/01/2003 - "The subsequent panel (cytokeratin AE1/3, cytokeratin 18, and HMB-45) helped to rule out a malignant melanoma and aided to settle the diagnosis of a metastatic carcinoma. "
10/01/1997 - "These genes included the rat homologues of human galectin-7 gene, the human/mouse melanoma inhibitory activity/bovine chondrocyte-derived retinoic acid sensitive protein gene, the mouse stearoyl-CoA desaturase-2 gene, and the mouse endo B cytokeratin/human cytokeratin-18 gene. "
06/01/2008 - "To this end, we collected clinical, pathologic, and molecular data for 65 uveal melanomas, including patient age, sex, tumor size, location, cell type, vasculogenic mimicry looping matrix patterns, gene expression profiles, and immunohistochemistry for cytokeratin-18, vascular endothelial cadherin, E-cadherin, beta-catenin, and hypoxia-inducible factor 1alpha. "
|1.||Non-alcoholic Fatty Liver Disease
|4.||Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
|5.||fibroblast growth factor 21
|7.||Biological Markers (Surrogate Marker)
|1.||Heterologous Transplantation (Xenotransplantation)
|2.||Drug Therapy (Chemotherapy)