Keratin-13 (Keratin 13)

08/01/2021 - "Whereas the homeostasis and repair functions of TRMØs were affected from up-regulated genes, such as over-expressed keratin-13 that helped form the outer keratinising squamous epithelial layer, and over-expressed MMPs that activated the extracellular matrix molecules to promote inflammation and disturb tissue remodeling. "

02/01/2023 - "Cytokeratin 13 (CK13) expression in cancer: a tissue microarray study on 10,439 tumors."
07/01/2010 - "A novel finding in our study was enhanced expression of keratin 13 in SCC, a result validated by immunohistochemical staining of an SCC tumor tissue array."
10/01/2007 - "The aim of the study was the pathological and immunohistochemical analysis of cytokeratin 13 (CK13) in intraepithelial cervical tumors. "
01/01/2016 - "Keratin 13 Is Enriched in Prostate Tubule-Initiating Cells and May Identify Primary Prostate Tumors that Metastasize to the Bone."
01/01/2015 - "Gradual loss of cytokeratin 13 (CK13) may be linked with the severity of dysplastic changes and transformation to malignancy. "

05/01/2002 - "[Studies of the deletion and expression of cytokeratin 13 gene in laryngeal squamous cell carcinoma]."
12/20/2014 - "Although the loss of keratin 13 (KRT13) is reportedly linked to malignant transformation of oral epithelial cells, the molecular mechanisms through which KRT13 is repressed in oral squamous cell carcinoma (OSCC) remain unclear. "
12/20/2014 - "Epigenetic alterations of the keratin 13 gene in oral squamous cell carcinoma."
08/01/2005 - "To investigate the expression and its significance of cytokeratin 13 gene in oral squamous cell carcinoma (OSCC). "
08/01/2005 - "[Expression and significance of cytokeratin 13 gene in oral squamous cell carcinoma]."

12/01/2020 - "Keratin 13 deficiency causes white sponge nevus in mice."
01/01/2017 - "A novel keratin 13 variant in a four-generation family with white sponge nevus."
12/01/2014 - "Keratin 13 mutations associated with oral white sponge nevus in two Chinese families."
11/01/2003 - "We identified a novel heterozygous missense mutation at 332T>C in the keratin 13 gene believed to be related to the development of white sponge nevus."
11/01/2003 - "Constitutional mutation of keratin 13 gene in familial white sponge nevus."

07/01/1995 - "A study of histochemical markers showed that gamma-glutamyltranspeptidase (GGT) and keratin 13, although good markers of malignant changes in early papillomas produced by two-stage carcinogenesis protocols, were mainly negative in dysplastic lesions produced by complete carcinogenesis with B[a]P. "
09/01/1997 - "Beginning with very early papillomas (after 10 wk of promotion), expression of alpha6beta4 in suprabasal cells and small, focal staining for keratin 13 (K13) were seen in some tumors. "
09/01/1999 - "D/T/D/T papillomas exhibited increases in suprabasal S phase cells and keratin 13 expression when compared with D/T/A/T papillomas. "
10/15/1993 - "When tumors first appeared at 8 weeks after promotion, high risk papillomas demonstrated basal and suprabasal alpha 6 beta 4 expression, loss of keratin 1, and aberrant expression of keratin 13. "
09/01/1991 - "Polymerase chain reaction analysis of DNA extracted from papillomas devoid of stromal contamination by fluorescence-activated sorting of single cell dispersions immunolabeled with anti-keratin 13 antibody revealed loss of heterozygosity at the Hbb locus, demonstrating that this event occurs during premalignant stages of tumor development. "