|1.||Nagano, Hiroaki: 2 articles (02/2008 - 01/2007)|
|2.||Monden, Morito: 2 articles (02/2008 - 01/2007)|
|3.||Yamamoto, Hirofumi: 2 articles (02/2008 - 01/2007)|
|4.||Dono, Keizo: 2 articles (02/2008 - 01/2007)|
|5.||Kondo, Motoi: 2 articles (02/2008 - 01/2007)|
|6.||Lee, Hye Jeong: 1 article (05/2015)|
|7.||Moon, Ji Wook: 1 article (05/2015)|
|8.||Kim, Hyeon Soo: 1 article (05/2015)|
|9.||Lee, Yong Woo: 1 article (05/2015)|
|10.||Kim, Nami: 1 article (05/2015)|
|1.||Melanoma (Melanoma, Malignant)
01/01/2011 - "Membrane-type-3 matrix metalloproteinase (MT3-MMP) functions as a matrix composition-dependent effector of melanoma cell invasion."
06/01/2001 - "The results indicate that MT3-MMP possesses the potential to promote melanoma invasion and proteolysis and that the formation of a complex between MT3-MMP and MCSP may be a crucial step in activating these processes."
05/01/2007 - "Co-immunoprecipitation studies suggest that MCSP forms a complex with MT3-MMP and MMP-2 on melanoma cell surface. "
01/01/2011 - "Consistently, MT3-MMP overexpression in cells derived from less advanced superficially spreading melanoma lesions, or in the MT3-MMP knockdown cells, reduced MT1-MMP-dependent collagen invasion. "
01/01/2011 - "In melanoma cell lines originating from advanced primary or metastatic lesions, endogenous MT3-MMP expression was associated with limited collagen-invasive potential. "
05/01/2015 - "The methylation status and expression levels of MT3-MMP were investigated in primary tumor tissues and adjacent normal tissues in 105 patients with CRC, one normal colon cell line (CCD18Co), and three CRC cell lines (SW480, DLD-1, and LoVo) by quantitative methylation-specific PCR and real-time PCR. "
06/16/2009 - "MT3-MMP is a matrix metalloproteinase involved in the regulation of cancer cell invasion and metastasis. "
12/01/2004 - "Neither human nor mouse MT2-MMP were correlated with tumor progression and MT3-MMP levels were negligible. "
01/01/2011 - "Since MT3-MMP was significantly upregulated in biopsies of human melanoma metastases, these results identify MT3-MMP as a matrix-dependent modifier of the invasive tumor cell functions during melanoma progression."
01/01/2011 - "By contrast, as a potent fibrinolytic enzyme, MT3-MMP induced efficient invasion of the cells in fibrin, a provisional matrix component frequently found at tumor-host tissue interfaces and perivascular spaces of melanoma. "
|3.||Glioblastoma (Glioblastoma Multiforme)
10/15/2006 - "Microarray studies showed no increase in these ECM factors, rather down-regulation of urokinase-type plasminogen activator and matrix metalloproteinase 16 in glioblastoma cells treated with OA-5D5. "
02/01/1999 - "MT3-MMP is detectable in both astrocytic tumor and normal brain tissues, but the mean expression level is approximately 50-fold lower compared with that of MT1-MMP and MT2-MMP in the glioblastomas. "
|4.||Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
12/01/2003 - "Immunohistochemical and in situ hybridization studies of the expression of the direct activators of MMP-2, MT1-MMP and MT3-MMP, and the indirect activation system tissue plasminogen activator, urokinase (u-PA), its receptor (u-PAR), and its inhibitor PAI-1 after middle cerebral artery occlusion/reperfusion were undertaken in basal ganglia samples from 26 adolescent male baboons. "
|5.||Pancreatic Neoplasms (Pancreatic Cancer)
01/01/2000 - "In the present study, we examined the role of MMP-2 and its activators MT1-MMP, MT2-MMP and MT3-MMP in pancreatic tumor cell invasion and the development of the desmoplastic reaction characteristic of pancreatic cancer tissues. "
01/01/2000 - "Northern blot analyses revealed that transcript levels of MT1-MMP and MT2-MMP, but not MT3-MMP, were enhanced in pancreatic cancer tissues (n = 18) compared with both chronic pancreatitis (n = 9) and healthy pancreas (n = 9). "
|1.||Matrix Metalloproteinase 14 (MT1-MMP)
|2.||Matrix Metalloproteinase 15
|3.||Urokinase-Type Plasminogen Activator (Urokinase)
|6.||Plasminogen Activator Inhibitor 1
|7.||Tissue Plasminogen Activator (Alteplase)
|9.||Messenger RNA (mRNA)
|10.||Collagen Type I (Type I Collagen)
|1.||Heterologous Transplantation (Xenotransplantation)