HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

Matrix Metalloproteinase 16

A transmembrane domain-containing matrix metalloproteinase. It is synthesized as an inactive zymogen that is activated by the proteolytic action of PROPROTEIN CONVERTASES. Matrix metalloproteinase 16 plays a direct role in the cleavage of proteins in the pericellular environment. In addition it can function indirectly by enzymatically activating the proprotein form of other MATRIX METALLOPROTEINASES such as the zymogen of MATRIX METALLOPROTEINASE 2.
Also Known As:
MMP-16 Metalloproteinase; MMP-X2 Protein; MMP16 Metalloproteinase; MT3-MMP; MT3-Matrix Metalloproteinase; Membrane-Type 3 Matrix Metalloproteinase; Membrane-Type Matrix Metalloproteinase 3; Membrane-Type-3 Matrix Metalloproteinase; MMP 16 Metalloproteinase; MMP X2 Protein; MT3 Matrix Metalloproteinase; Matrix Metalloproteinase, Membrane-Type-3; Membrane Type 3 Matrix Metalloproteinase; Membrane Type Matrix Metalloproteinase 3; Metalloproteinase, MMP-16; Metalloproteinase, MMP16; Metalloproteinase, Membrane-Type-3 Matrix
Networked: 31 relevant articles (0 outcomes, 5 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Nagano, Hiroaki: 2 articles (02/2008 - 01/2007)
2. Monden, Morito: 2 articles (02/2008 - 01/2007)
3. Yamamoto, Hirofumi: 2 articles (02/2008 - 01/2007)
4. Dono, Keizo: 2 articles (02/2008 - 01/2007)
5. Kondo, Motoi: 2 articles (02/2008 - 01/2007)
6. Lee, Hye Jeong: 1 article (05/2015)
7. Moon, Ji Wook: 1 article (05/2015)
8. Kim, Hyeon Soo: 1 article (05/2015)
9. Lee, Yong Woo: 1 article (05/2015)
10. Kim, Nami: 1 article (05/2015)

Related Diseases

1. Melanoma (Melanoma, Malignant)
2. Neoplasms (Cancer)
3. Glioblastoma (Glioblastoma Multiforme)
4. Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
5. Pancreatic Neoplasms (Pancreatic Cancer)

Related Drugs and Biologics

1. Matrix Metalloproteinase 14 (MT1-MMP)
2. Matrix Metalloproteinase 15
3. Urokinase-Type Plasminogen Activator (Urokinase)
4. Carbon Monoxide
5. Matrix Metalloproteinases
6. Plasminogen Activator Inhibitor 1
7. Tissue Plasminogen Activator (Alteplase)
8. Antibodies
9. Messenger RNA (mRNA)
10. Collagen Type I (Type I Collagen)

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)