|1.||Shapiro, Steven D: 6 articles (10/2011 - 09/2002)|
|2.||Shi, Hai: 3 articles (01/2012 - 02/2006)|
|3.||Mei, Qiao: 3 articles (01/2012 - 02/2006)|
|4.||Fan, Jianglin: 3 articles (05/2008 - 10/2004)|
|5.||Watanabe, Teruo: 3 articles (05/2008 - 10/2004)|
|6.||Imamura, M: 3 articles (09/2001 - 05/2000)|
|7.||Arii, S: 3 articles (09/2001 - 05/2000)|
|8.||Gorrin-Rivas, M J: 3 articles (09/2001 - 05/2000)|
|9.||Mori, A: 3 articles (09/2001 - 05/2000)|
|10.||Pellicoro, Antonella: 2 articles (06/2012 - 01/2012)|
01/01/2012 - "Recent evidence implicates macrophage metalloelastase (MMP-12), a macrophage-derived elastinolytic protease in inflammation, tissue remodeling and angiogenesis. "
08/01/2006 - "Role of macrophage metalloelastase in gut inflammation."
04/05/2009 - "These results were significantly different from those of Uf-NiO particles which induced high expression of genes associated with chemokines, oxidative stress, and matrix metalloproteinase 12 (Mmp12), suggesting that Uf-NiO particles lead to acute inflammation for the inhalation exposure period, and the damaged tissues were repaired in the post-exposure period. "
01/01/2012 - "Macrophage metalloelastase (MMP-12) deficiency mitigates retinal inflammation and pathological angiogenesis in ischemic retinopathy."
05/01/2013 - "TSLP treatment in IL-4Rα1-deficient mice promoted similar cutaneous inflammation as in wild-type mice, though TSLP-induced arginase 1, CCL2, and matrix metalloproteinase 12 messenger RNA levels were blocked. "
09/01/2007 - "Macrophage Metalloelastase (HME) plays an important role in tumor growth, infiltration and metastasis. "
03/01/2001 - "Macrophage metalloelastase (MMP-12) is implicated in the pathology of many diseases such as emphysema, aortic lesions and cancer. "
05/01/2000 - "Mouse macrophage metalloelastase gene transfer into a murine melanoma suppresses primary tumor growth by halting angiogenesis."
01/01/2012 - "Previous studies have shown that overexpression of macrophage metalloelastase (MME) suppresses tumor growth in mice. "
10/01/1998 - "Macrophage metalloelastase, a member of the human matrix metalloproteinase family, is believed to play an important role in angiostatin generation, which, in experimental studies, has an antiangiogenic function and is a key molecule in tumor dormancy. "
|3.||Chronic Obstructive Pulmonary Disease (COPD)
01/01/2005 - "Thus, we analyzed the expression and release of MMP-12 (macrophage metalloelastase) in bronchoalveolar lavage (BAL) and lung tissue from COPD patients and control subjects. "
12/31/2009 - "Matrix metalloproteinase 12, asthma, and COPD."
09/01/2012 - "In a previous study, we reported that Pneumocystis-colonized HIV-positive subjects had worse obstruction of airways and higher sputum levels of macrophage elastase/matrix metalloproteinase 12 (MMP12), a protease strongly associated with the development of COPD. "
10/01/2010 - "The catalytic domain of metalloelastase (matrix metalloproteinase-12 or MMP-12) is unique among MMPs in exerting high proteolytic activity upon fibrils that resist hydrolysis, especially elastin from lungs afflicted with chronic obstructive pulmonary disease or arteries with aneurysms. "
05/01/2003 - "Our present study supports the previous report that macrophage metalloelastase is related to ulcer formation of UC, and it also indicates the possibility that osteopontin plays an important role in the pathogenesis of UC via increased immune activity."
05/01/2003 - "It has been said that macrophage metalloelastase is related to ulcer formation of the intestine, whereas osteopontin plays an important role in the pathogenesis of systemic lupus erythematosus and rheumatoid arthritis. "
01/01/2003 - "aeruginosa, expressing the major metalloproteinase elastase, induces degradation of complement C3, various antiproteinases, kininogens, fibroblast proteins, and proteoglycans (PG) in vitro, thus mimicking proteolytic activity previously identified in chronic ulcer fluid in vivo. "
|5.||Systemic Scleroderma (Systemic Sclerosis)
08/01/2010 - "Studies have shown that in systemic sclerosis (SSc) endothelial cells, overproduction of matrix metalloproteinase 12 (MMP-12) and pentraxin 3 (PTX3) is associated with defective angiogenesis. "
08/01/2010 - "Modulation of the angiogenic phenotype of normal and systemic sclerosis endothelial cells by gain-loss of function of pentraxin 3 and matrix metalloproteinase 12."
|5.||Pancreatic Elastase (Elastase)
|10.||Messenger RNA (mRNA)