|1.||Hummler, Edith: 10 articles (12/2015 - 01/2002)|
|2.||Rossier, Bernard C: 8 articles (11/2010 - 01/2002)|
|3.||Schild, Laurent: 7 articles (12/2010 - 01/2002)|
|4.||Korbmacher, Christoph: 6 articles (04/2010 - 03/2004)|
|5.||He, Jing: 5 articles (02/2015 - 11/2012)|
|6.||Deng, Wang: 5 articles (02/2015 - 05/2011)|
|7.||Knepper, Mark A: 5 articles (12/2007 - 05/2003)|
|8.||Zhao, Yan: 4 articles (02/2015 - 11/2012)|
|9.||Zhao, Dan: 4 articles (01/2015 - 06/2011)|
|10.||Boucher, Richard C: 4 articles (06/2014 - 12/2004)|
|1.||Hypertension (High Blood Pressure)
09/01/2005 - "Improvement in blood pressure with inhibition of the epithelial sodium channel in blacks with hypertension."
11/01/2014 - "We examined the associations of epithelial sodium channel (ENaC) genes with blood pressure (BP) changes and hypertension incidence in a longitudinal family study. "
11/01/2014 - "Associations of epithelial sodium channel genes with blood pressure changes and hypertension incidence: the GenSalt study."
11/01/2014 - "The purpose of this study was to investigate whether common polymorphisms in the C-terminus of SCNN1B gene encoding the β-subunit of epithelial sodium channel are associated with essential hypertension (EH) in Chinese hypertensive families. "
04/01/2012 - "This study aimed to screen the gene mutation in β and γ subunits of the epithelial sodium channel (ENaC) of a Chinese family with Liddle's syndrome, an autosomal dominant form of hypertension. "
01/01/2015 - "Initially, upregulation of the epithelial sodium channel (ENaC) in the collecting ducts by TZDs was thought to be the primary cause of edema. "
12/01/2013 - "Mechanism of action of novel lung edema therapeutic AP301 by activation of the epithelial sodium channel."
09/21/2012 - "Removal of edema from the air spaces of lung is a critical function of the epithelial sodium channel (ENaC) in ALI. "
01/01/2012 - "Stimulation of epithelial sodium channel (ENaC) increases Na(+) transport, a driving force of alveolar fluid clearance (AFC) to keep alveolar spaces free of edema fluid that is beneficial for acute lung injury (ALI). "
01/01/2015 - "Electroporation-mediated gene delivery of epithelial sodium channel (ENaC) and Na+,K+ -ATPase into alveolar cells would improve alveolar clearance of edema and attenuate ARDS. "
|3.||Acute Lung Injury
01/21/2014 - "TGF-β directs trafficking of the epithelial sodium channel ENaC which has implications for ion and fluid transport in acute lung injury."
01/01/2014 - "17β-estradiol can suppress acute lung injury (ALI) and regulate alveolar epithelial sodium channel (ENaC). "
01/01/2014 - "17β-estradiol suppresses lipopolysaccharide-induced acute lung injury through PI3K/Akt/SGK1 mediated up-regulation of epithelial sodium channel (ENaC) in vivo and in vitro."
11/01/2012 - "To investigate the effect of astragali injection on the expression of epithelial sodium channel in mice with acute lung injury (ALI) and explore the possible mechanism. "
11/01/2012 - "[Effect of astragali injection on epithelial sodium channel expression in mice with acute lung injury]."
10/01/2015 - "Therefore, the present study is designed to evaluate the role of epithelial sodium channel (ENaC) in H2S-induced acute pulmonary edema. "
10/01/2015 - "Epithelial sodium channel is involved in H2S-induced acute pulmonary edema."
02/01/2015 - "Stimulation of epithelial sodium channel (ENaC) promotes Na(+) transport, a rate-limiting step for pulmonary edema reabsorption. "
01/21/2014 - "A unique TGF-β pathway is described, which rapidly promoted internalization of the αβγ epithelial sodium channel (ENaC) complex from the alveolar epithelial cell surface, leading to persistence of pulmonary edema. "
01/01/2014 - "The epithelial sodium channel (ENaC) is the driving force for pulmonary edema absorption in acute lung injury (ALI). "
|5.||Cystic Fibrosis (Mucoviscidosis)
09/21/2012 - "Recent studies suggest that misregulation of protease activity in the cystic fibrosis lung may alter fluid secretion and pathogen clearance by proteolytic activation of the epithelial sodium channel (ENaC). "
01/01/2015 - "Direct interactions between ENaC gamma subunit and ClCN2 in cystic fibrosis epithelial cells."
06/01/2014 - "Inhaled epithelial sodium channel (ENaC) blockers are designed to increase airway surface liquid volume, thereby benefiting cystic fibrosis patients. "
01/01/2014 - "Cystic fibrosis transmembrane conductance regulators (CFTR) and epithelial sodium channel alpha subunits (ENaC-α) play an important role in female reproduction by maintaining humoral and cell homeostasis. "
01/01/2014 - "Increased cystic fibrosis transmembrane conductance regulators expression and decreased epithelial sodium channel alpha subunits expression in early abortion: findings from a mouse model and clinical cases of abortion."
|1.||Sodium Channel Blockers (Potassium Sparing Diuretics)
|2.||Adenosine Triphosphatases (ATPase)
|3.||Matrix Metalloproteinase 7 (Matrilysin)
|4.||Guanidine (Guanidine Nitrate)
|6.||methanesulfonic acid (methanesulfonate)
|9.||Ion Channels (Ion Channel)
|3.||Positive-Pressure Respiration (PEEP)