|1.||Sallenave, Jean-Michel: 13 articles (01/2015 - 09/2003)|
|2.||Zani, Marie-Louise: 5 articles (01/2015 - 06/2004)|
|3.||Moreau, Thierry: 5 articles (01/2015 - 06/2004)|
|4.||Schalkwijk, Joost: 5 articles (05/2011 - 05/2002)|
|5.||Sallenave, J M: 5 articles (07/2008 - 01/2000)|
|6.||Bourbonnais, Yves: 5 articles (08/2007 - 02/2002)|
|7.||Tremblay, Guy M: 5 articles (08/2007 - 02/2002)|
|8.||Rabinovitch, Marlene: 4 articles (06/2015 - 01/2002)|
|9.||Motta, Jean-Paul: 4 articles (01/2015 - 04/2011)|
|10.||Vergnolle, Nathalie: 4 articles (01/2015 - 04/2011)|
08/01/2012 - "Studies also linked Trappin-2/Elafin to either susceptibility or protection against inflammatory disease and infections, even though the mechanisms remains poorly understood. "
01/01/2013 - "pylori infection was associated with increased gastric levels of the inducible defensin HBD2 and of the antiprotease elafin, whereas the expression levels of the constitutive defensin HBD1, inducible HBD3 and LL37 remained unchanged. "
04/01/2012 - "The reduced concentrations of SLPI and ELAFIN may contribute to the loss of host protective capacity and increase susceptibility to breakdown from chronic infection. "
02/01/2010 - "The inhibitory activity was observed when virus was incubated with Trappin-2/Elafin but not when Trappin-2/Elafin was added to cells either before infection or after infection. "
04/01/2002 - "In addition, we have shown, using an adenovirus-mediated gene transfer overexpression strategy, that elafin is also active against Pseudomonas aeruginosa infection in mice in vivo. "
01/07/2015 - "Because plasma elafin levels correlate with skin GVHD, this study examined urinary elafin as a potential marker of renal inflammation and injury. "
10/01/2011 - "Phase II trials are underway to investigate the therapeutic effects of elafin on post-operative inflammation and the clinical consequences of major surgery. "
01/01/2015 - "Strikingly, a higher reduction of intestinal inflammation in DSS-treated mice was observed with the Elafin-overproducing htrA strain suggesting a dose-dependent Elafin effect. "
04/01/2013 - "This loss of elafin may predispose people, in part, to excessive inflammation in ALI."
10/31/2012 - "Food-grade bacteria expressing elafin protect against inflammation and restore colon homeostasis."
01/01/2015 - "In addition, GG-elafin showed improved anti-inflammatory activity in a mouse model of LPS-induced acute lung inflammation. "
01/01/2015 - "A functional variant of elafin with improved anti-inflammatory activity for pulmonary inflammation."
07/01/2002 - "Anti-inflammatory effect of pre-elafin in lipopolysaccharide-induced acute lung inflammation."
07/01/2002 - "The aim of the present study was to evaluate the anti-inflammatory activity of pre-elafin, an elastase-specific inhibitor, in lipopolysaccharide (LPS)-induced acute lung inflammation. "
07/20/2001 - "Selective augmentation of host defense molecules such as elafin (an elastase inhibitor with antimicrobial activity) at the onset of pulmonary inflammation is an attractive potential therapeutic strategy. "
04/01/2011 - "In mice given TNBS or DSS, transgenic expression of elafin or disruption of NE and PR-3 protected against the development of colitis. "
04/01/2011 - "Modifying the protease, antiprotease pattern by elafin overexpression protects mice from colitis."
01/01/2013 - "A few natural AMPs were shown to be able to modulate colitis when delivered intravenously or intracolonically (cathelicidin, elafin and SLPI) in mouse colitis models. "
10/31/2012 - "In mouse models of acute and chronic colitis, oral administration of Elafin-expressing LAB decreased elastolytic activity and inflammation and restored intestinal homeostasis. "
04/01/2011 - "The protease inhibitor Elafin prevents intestinal inflammation in mouse models of colitis and might be developed as a therapeutic agent for inflammatory bowel disease."
07/01/2004 - "Elafin-overexpressing mice have improved cardiac function after myocardial infarction."
10/01/2015 - "Elafin had no effect on myocardial infarction (elafin, 7/34 vs placebo, 5/35 patients) or on markers of inflammation: mean differences for AUC hs-CRP of 499 mg/L/48 h (95% CI -207 to 1205, p=0.16), and AUC MPO of 238 ng/mL/48 h (95% CI -235 to 711, p=0.320). "
07/01/2004 - "We therefore assessed the effects of overexpressing the selective serine elastase inhibitor elafin in transgenic mice in which a myocardial infarction was caused by ligation of the left anterior descending coronary artery (LAD). "
|1.||Secretory Leukocyte Peptidase Inhibitor
|3.||Serine Proteinase Inhibitors (Serine Protease Inhibitors)
|7.||Pancreatic Elastase (Elastase)
|8.||Serine Proteases (Serine Protease)
|9.||Biological Markers (Surrogate Marker)
|2.||Coronary Artery Bypass (Coronary Artery Bypass Surgery)
|3.||Heterologous Transplantation (Xenotransplantation)
|4.||Heart Transplantation (Grafting, Heart)
|5.||Bone Marrow Transplantation (Transplantation, Bone Marrow)