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Nod1 Signaling Adaptor Protein

A NOD-signaling adaptor protein that contains a C-terminal leucine-rich domain which recognizes bacterial PEPTIDOGLYCAN. It signals via an N-terminal caspase recruitment domain that interacts with other CARD SIGNALING ADAPTOR PROTEINS such as RIP SERINE-THEONINE KINASES. It plays a role in the host defense response by signaling the activation of CASPASES and the MAP KINASE SIGNALING SYSTEM.
Also Known As:
CARD4 Protein; Caspase Recruitment Domain Protein 4; Nucleotide Oligomerization Domain 1 Protein
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